Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13004.174 | 0.0003 | -0.8406 | 3.2757 | |
| SUM159PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13054.174 | 0.9673 | 0.9788 | 3.1161 | |
| SUM159PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13054.174 | 0.9604 | 0.9742 | 3.1161 | |
| SUM159PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13054.174 | 0.9887 | 0.9927 | 3.1161 | |
| SUM159PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13054.174 | 1.0557 | 1.0351 | 3.1161 | |
| SUM159PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13054.174 | 0.6238 | 0.7189 | 3.1161 | |
| SUM159PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13054.174 | 0.1898 | 0.1733 | 3.1161 | |
| SUM159PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13054.174 | 0.2964 | 0.3538 | 3.1161 | |
| SUM159PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13054.174 | 0.4616 | 0.5605 | 3.1161 | |
| SUM159PT | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13054.174 | 0.3684 | 0.4517 | 3.1161 | |
| SUM185PE | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13140.174 | 0.9685 | 0.8921 | 0.5769 | |
| SUM185PE | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13140.174 | 0.9651 | 0.8807 | 0.5769 | |
| SUM185PE | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13140.174 | 1.0057 | 1.0199 | 0.5769 | |
| SUM185PE | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13140.174 | 1.0161 | 1.0560 | 0.5769 | |
| SUM185PE | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13140.174 | 0.9431 | 0.8069 | 0.5769 | |
| SUM185PE | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13140.174 | 0.9661 | 0.8841 | 0.5769 | |
| SUM185PE | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13140.174 | 0.9165 | 0.7194 | 0.5769 | |
| SUM185PE | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13140.174 | 0.9591 | 0.8603 | 0.5769 | |
| SUM185PE | TNBC | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13140.174 | 0.8652 | 0.5561 | 0.5769 | |
| SUM229PE | TNBC | - | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13009.174 | 0.9835 | 0.9765 | 1.4104 | |
| SUM229PE | TNBC | - | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13009.174 | 0.9836 | 0.9766 | 1.4104 | |
| SUM229PE | TNBC | - | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13009.174 | 0.9977 | 0.9967 | 1.4104 | |
| SUM229PE | TNBC | - | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13009.174 | 1.0044 | 1.0062 | 1.4104 | |
| SUM229PE | TNBC | - | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13009.174 | 0.9724 | 0.9607 | 1.4104 | |
| SUM229PE | TNBC | - | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13009.174 | 0.9376 | 0.9107 | 1.4104 |