Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12612.174 | 0.9793 | 0.9310 | 0.5962 | |
| HCC1419 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12612.174 | 0.9679 | 0.8934 | 0.5962 | |
| HCC1419 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12612.174 | 0.9508 | 0.8378 | 0.5962 | |
| HCC1419 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12612.174 | 0.9601 | 0.8678 | 0.5962 | |
| HCC1419 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12612.174 | 0.9338 | 0.7829 | 0.5962 | |
| HCC1419 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12612.174 | 0.8666 | 0.5729 | 0.5962 | |
| HCC1428 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13107.174 | 0.9739 | 0.9229 | 0.6723 | |
| HCC1428 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13107.174 | 0.9677 | 0.9047 | 0.6723 | |
| HCC1428 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13107.174 | 0.9871 | 0.9617 | 0.6723 | |
| HCC1428 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13107.174 | 0.9704 | 0.9126 | 0.6723 | |
| HCC1428 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13107.174 | 0.9414 | 0.8282 | 0.6723 | |
| HCC1428 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13107.174 | 0.7688 | 0.3527 | 0.6723 | |
| HCC1428 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13107.174 | 0.9083 | 0.7333 | 0.6723 | |
| HCC1428 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13107.174 | 0.8664 | 0.6159 | 0.6723 | |
| HCC1428 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13107.174 | 0.7087 | 0.1983 | 0.6723 | |
| HCC1569 | HER2amp | Basal A | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13038.174 | 0.9566 | 0.9276 | 1.2027 | |
| HCC1569 | HER2amp | Basal A | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13038.174 | 1.0113 | 1.0187 | 1.2027 | |
| HCC1569 | HER2amp | Basal A | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13038.174 | 0.9999 | 0.9998 | 1.2027 | |
| HCC1569 | HER2amp | Basal A | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13038.174 | 0.9921 | 0.9869 | 1.2027 | |
| HCC1569 | HER2amp | Basal A | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13038.174 | 0.8056 | 0.6710 | 1.2027 | |
| HCC1569 | HER2amp | Basal A | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13038.174 | 0.4772 | 0.0812 | 1.2027 | |
| HCC1569 | HER2amp | Basal A | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13038.174 | 0.7015 | 0.4894 | 1.2027 | |
| HCC1569 | HER2amp | Basal A | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13038.174 | 0.8642 | 0.7714 | 1.2027 | |
| HCC1569 | HER2amp | Basal A | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13038.174 | 0.9140 | 0.8560 | 1.2027 | |
| HCC1806 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12702.174 | 0.9514 | 0.9468 | 1.8506 |