Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12702.174 | 0.9835 | 0.9821 | 1.8506 | |
| HCC1806 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12702.174 | 0.9595 | 0.9559 | 1.8506 | |
| HCC1806 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12702.174 | 0.9863 | 0.9851 | 1.8506 | |
| HCC1806 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12702.174 | 0.9404 | 0.9346 | 1.8506 | |
| HCC1806 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12702.174 | 0.2439 | -0.0669 | 1.8506 | |
| HCC1806 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12702.174 | 0.3955 | 0.2115 | 1.8506 | |
| HCC1806 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12702.174 | 0.5959 | 0.5119 | 1.8506 | |
| HCC1806 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12702.174 | 0.4945 | 0.3670 | 1.8506 | |
| HCC1937 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13115.174 | 0.9462 | 0.8684 | 0.8122 | |
| HCC1937 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13115.174 | 1.0032 | 1.0078 | 0.8122 | |
| HCC1937 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13115.174 | 1.0017 | 1.0041 | 0.8122 | |
| HCC1937 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13115.174 | 1.0155 | 1.0383 | 0.8122 | |
| HCC1937 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13115.174 | 0.6512 | 0.1795 | 0.8122 | |
| HCC1937 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13115.174 | 0.3746 | -0.4030 | 0.8122 | |
| HCC1937 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13115.174 | 0.7553 | 0.4156 | 0.8122 | |
| HCC1937 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13115.174 | 0.7137 | 0.3203 | 0.8122 | |
| HCC1937 | TNBC | Basal A | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13115.174 | 0.1614 | -0.7883 | 0.8122 | |
| HCC1954 | HER2amp | Basal A | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13546.174 | 1.0116 | 1.0193 | 1.2035 | |
| HCC1954 | HER2amp | Basal A | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13546.174 | 0.9428 | 0.9046 | 1.2035 | |
| HCC1954 | HER2amp | Basal A | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13546.174 | 1.0059 | 1.0097 | 1.2035 | |
| HCC1954 | HER2amp | Basal A | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13546.174 | 1.0641 | 1.1060 | 1.2035 | |
| HCC1954 | HER2amp | Basal A | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13546.174 | 1.0087 | 1.0145 | 1.2035 | |
| HCC1954 | HER2amp | Basal A | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13546.174 | 0.9039 | 0.8390 | 1.2035 | |
| HCC1954 | HER2amp | Basal A | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13546.174 | 0.9596 | 0.9326 | 1.2035 | |
| HCC1954 | HER2amp | Basal A | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13546.174 | 0.9786 | 0.9643 | 1.2035 |