Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12632.174 | 0.1517 | -0.7789 | 0.8563 | |
| MDA-MB-157 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12632.174 | 0.0102 | -0.9906 | 0.8563 | |
| MDA-MB-175-VII | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13754.174 | 0.9728 | 0.8755 | 0.4290 | |
| MDA-MB-175-VII | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13754.174 | 0.9663 | 0.8464 | 0.4290 | |
| MDA-MB-175-VII | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13754.174 | 1.0027 | 1.0125 | 0.4290 | |
| MDA-MB-175-VII | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13754.174 | 0.9864 | 0.9372 | 0.4290 | |
| MDA-MB-175-VII | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13754.174 | 0.8042 | 0.2035 | 0.4290 | |
| MDA-MB-175-VII | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 13754.174 | 0.5316 | -0.5414 | 0.4290 | |
| MDA-MB-175-VII | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 13754.174 | 0.7901 | 0.1548 | 0.4290 | |
| MDA-MB-175-VII | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 13754.174 | 0.7769 | 0.1105 | 0.4290 | |
| MDA-MB-175-VII | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 13754.174 | 0.6496 | -0.2683 | 0.4290 | |
| MDA-MB-361 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12989.174 | 0.9723 | 0.9223 | 0.7084 | |
| MDA-MB-361 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12989.174 | 0.9959 | 0.9884 | 0.7084 | |
| MDA-MB-361 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12989.174 | 0.9759 | 0.9323 | 0.7084 | |
| MDA-MB-361 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12989.174 | 0.9854 | 0.9589 | 0.7084 | |
| MDA-MB-361 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12989.174 | 0.5437 | -0.1538 | 0.7084 | |
| MDA-MB-361 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12989.174 | 0.2268 | -0.7537 | 0.7084 | |
| MDA-MB-361 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12989.174 | 0.7416 | 0.3115 | 0.7084 | |
| MDA-MB-361 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12989.174 | 0.3710 | -0.5066 | 0.7084 | |
| MDA-MB-361 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12989.174 | 0.0003 | -1.0000 | 0.7084 | |
| MDA-MB-361 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 13558.174 | 0.9543 | 0.8424 | 0.5699 | |
| MDA-MB-361 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 13558.174 | 0.9551 | 0.8449 | 0.5699 | |
| MDA-MB-361 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 13558.174 | 0.9735 | 0.9078 | 0.5699 | |
| MDA-MB-361 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 13558.174 | 0.9830 | 0.9406 | 0.5699 | |
| MDA-MB-361 | HER2amp | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 13558.174 | 0.6458 | -0.0714 | 0.5699 |