Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12657.174 | 0.9571 | 0.9203 | 1.0776 | |
| MCF7 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12657.174 | 0.9771 | 0.9574 | 1.0776 | |
| MCF7 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12657.174 | 1.0005 | 1.0010 | 1.0776 | |
| MCF7 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12657.174 | 0.9940 | 0.9889 | 1.0776 | |
| MCF7 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12657.174 | 0.9653 | 0.9356 | 1.0776 | |
| MCF7 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12657.174 | 0.9102 | 0.8327 | 1.0776 | |
| MCF7 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12657.174 | 0.9705 | 0.9452 | 1.0776 | |
| MCF7 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12657.174 | 0.9145 | 0.8409 | 1.0776 | |
| MCF7 | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12657.174 | 0.4680 | -0.0114 | 1.0776 | |
| MDA-MB-134-VI | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12662.174 | 0.9260 | 0.9069 | 1.6130 | |
| MDA-MB-134-VI | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12662.174 | 0.9605 | 0.9506 | 1.6130 | |
| MDA-MB-134-VI | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12662.174 | 0.9666 | 0.9583 | 1.6130 | |
| MDA-MB-134-VI | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12662.174 | 0.9673 | 0.9591 | 1.6130 | |
| MDA-MB-134-VI | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12662.174 | 1.0052 | 1.0064 | 1.6130 | |
| MDA-MB-134-VI | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12662.174 | 0.4867 | 0.2797 | 1.6130 | |
| MDA-MB-134-VI | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12662.174 | 0.5465 | 0.3751 | 1.6130 | |
| MDA-MB-134-VI | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 13.3 | uM | 12662.174 | 0.6277 | 0.4985 | 1.6130 | |
| MDA-MB-134-VI | HR+ | Luminal | Disulfiram | Proteasome | Proteasome | 66.7 | uM | 12662.174 | 0.0147 | -0.8536 | 1.6130 | |
| MDA-MB-157 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.000171 | uM | 12632.174 | 0.9993 | 0.9983 | 0.8563 | |
| MDA-MB-157 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.000853 | uM | 12632.174 | 0.9521 | 0.8885 | 0.8563 | |
| MDA-MB-157 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.00427 | uM | 12632.174 | 0.9920 | 0.9814 | 0.8563 | |
| MDA-MB-157 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.0213 | uM | 12632.174 | 1.0100 | 1.0234 | 0.8563 | |
| MDA-MB-157 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.107 | uM | 12632.174 | 0.6559 | 0.2222 | 0.8563 | |
| MDA-MB-157 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 0.533 | uM | 12632.174 | 0.3410 | -0.4306 | 0.8563 | |
| MDA-MB-157 | TNBC | Basal B | Disulfiram | Proteasome | Proteasome | 2.67 | uM | 12632.174 | 0.5278 | -0.0518 | 0.8563 |