Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 1.38 | uM | 7804.017 | 0.0510 | -0.3645 | 2.5963 | |
| BT-549 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 6.9 | uM | 7804.017 | 0.0151 | -0.6019 | 2.5963 | |
| BT-549 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 34.5 | uM | 7804.017 | 0.0097 | -0.6639 | 2.5963 | |
| BT-549 | TNBC | Basal B | Epirubicin | TOP2 | TOP | 172 | uM | 7804.017 | 0.0003 | -0.9164 | 2.5963 | |
| HBL-100 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7807.017 | 1.0255 | 1.0230 | 2.2007 | |
| HBL-100 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7807.017 | 1.0349 | 1.0315 | 2.2007 | |
| HBL-100 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 0.011 | uM | 7807.017 | 1.0060 | 1.0054 | 2.2007 | |
| HBL-100 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7807.017 | 0.9102 | 0.9163 | 2.2007 | |
| HBL-100 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 0.276 | uM | 7807.017 | 0.2248 | 0.0151 | 2.2007 | |
| HBL-100 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 1.38 | uM | 7807.017 | 0.0080 | -0.7772 | 2.2007 | |
| HBL-100 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 6.9 | uM | 7807.017 | 0.0083 | -0.7730 | 2.2007 | |
| HBL-100 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 34.5 | uM | 7807.017 | 0.0072 | -0.7872 | 2.2007 | |
| HBL-100 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 172 | uM | 7807.017 | 0.0009 | -0.9194 | 2.2007 | |
| HBL-100 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7808.017 | 0.9895 | 0.9912 | 2.4168 | |
| HBL-100 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7808.017 | 0.9578 | 0.9646 | 2.4168 | |
| HBL-100 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 0.011 | uM | 7808.017 | 1.0966 | 1.0778 | 2.4168 | |
| HBL-100 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 0.0552 | uM | 7808.017 | 0.8672 | 0.8855 | 2.4168 | |
| HBL-100 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 0.276 | uM | 7808.017 | 0.1180 | -0.1740 | 2.4168 | |
| HBL-100 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 1.38 | uM | 7808.017 | 0.0250 | -0.5654 | 2.4168 | |
| HBL-100 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 6.9 | uM | 7808.017 | 0.0009 | -0.8898 | 2.4168 | |
| HBL-100 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 34.5 | uM | 7808.017 | 0.0005 | -0.9142 | 2.4168 | |
| HBL-100 | Unknown | Unknown | Epirubicin | TOP2 | TOP | 172 | uM | 7808.017 | 0.0005 | -0.9142 | 2.4168 | |
| HCC1143 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.000441 | uM | 7809.017 | 0.9658 | 0.9608 | 1.7591 | |
| HCC1143 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.00221 | uM | 7809.017 | 0.8775 | 0.8568 | 1.7591 | |
| HCC1143 | TNBC | Basal A | Epirubicin | TOP2 | TOP | 0.011 | uM | 7809.017 | 0.9838 | 0.9815 | 1.7591 |