Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7543.074 | 0.9533 | 0.9257 | 1.2642 | |
| T47D | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7543.074 | 0.8089 | 0.6910 | 1.2642 | |
| T47D | HR+ | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7543.074 | 0.5893 | 0.3163 | 1.2642 | |
| T47D | HR+ | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7543.074 | 0.3971 | -0.0367 | 1.2642 | |
| T47D | HR+ | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7543.074 | 0.3266 | -0.1748 | 1.2642 | |
| T47D | HR+ | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7543.074 | 0.3041 | -0.2200 | 1.2642 | |
| T47DKBLUC | Unknown | Unknown | Etoposide | TOP2 | TOP | 0.000853 | uM | 7546.074 | 1.0471 | 1.1118 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Etoposide | TOP2 | TOP | 0.00427 | uM | 7546.074 | 1.0537 | 1.1276 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Etoposide | TOP2 | TOP | 0.0213 | uM | 7546.074 | 1.0077 | 1.0181 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Etoposide | TOP2 | TOP | 0.107 | uM | 7546.074 | 1.0200 | 1.0474 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Etoposide | TOP2 | TOP | 0.533 | uM | 7546.074 | 0.9046 | 0.7766 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Etoposide | TOP2 | TOP | 2.67 | uM | 7546.074 | 0.6689 | 0.2436 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Etoposide | TOP2 | TOP | 13.3 | uM | 7546.074 | 0.5891 | 0.0704 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Etoposide | TOP2 | TOP | 66.7 | uM | 7546.074 | 0.5053 | -0.1071 | 0.8465 | |
| T47DKBLUC | Unknown | Unknown | Etoposide | TOP2 | TOP | 333 | uM | 7546.074 | 0.4570 | -0.2071 | 0.8465 | |
| ZR-75-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7552.074 | 1.0162 | 1.0354 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7552.074 | 0.9979 | 0.9953 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7552.074 | 0.9814 | 0.9596 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.107 | uM | 7552.074 | 0.9478 | 0.8865 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.533 | uM | 7552.074 | 0.9104 | 0.8055 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 2.67 | uM | 7552.074 | 0.6839 | 0.3217 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 13.3 | uM | 7552.074 | 0.5615 | 0.0660 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 66.7 | uM | 7552.074 | 0.4298 | -0.2033 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 333 | uM | 7552.074 | 0.3077 | -0.4465 | 0.9174 | |
| ZR-75-1 | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7553.074 | 1.0216 | 1.0453 | 0.9515 |