Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 2.67 | uM | 7495.074 | 0.7904 | 0.6365 | 1.1729 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 13.3 | uM | 7495.074 | 0.3941 | -0.0959 | 1.1729 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 66.7 | uM | 7495.074 | 0.0963 | -0.7280 | 1.1729 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 7495.074 | 0.0629 | -0.8109 | 1.1729 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.000853 | uM | 7496.074 | 0.9705 | 0.9562 | 1.3504 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.00427 | uM | 7496.074 | 0.9205 | 0.8810 | 1.3504 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.0213 | uM | 7496.074 | 0.8989 | 0.8482 | 1.3504 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.107 | uM | 7496.074 | 0.8271 | 0.7377 | 1.3504 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.533 | uM | 7496.074 | 0.6303 | 0.4209 | 1.3504 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 2.67 | uM | 7496.074 | 0.6729 | 0.4915 | 1.3504 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 13.3 | uM | 7496.074 | 0.3737 | -0.0351 | 1.3504 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 66.7 | uM | 7496.074 | 0.1037 | -0.6265 | 1.3504 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 7496.074 | 0.0718 | -0.7156 | 1.3504 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.000853 | uM | 7498.074 | 1.0092 | 1.0169 | 1.0877 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.00427 | uM | 7498.074 | 0.9679 | 0.9408 | 1.0877 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.0213 | uM | 7498.074 | 1.0281 | 1.0515 | 1.0877 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.107 | uM | 7498.074 | 0.9045 | 0.8236 | 1.0877 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 0.533 | uM | 7498.074 | 0.6711 | 0.3861 | 1.0877 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 2.67 | uM | 7498.074 | 0.7833 | 0.5978 | 1.0877 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 13.3 | uM | 7498.074 | 0.3438 | -0.2506 | 1.0877 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 66.7 | uM | 7498.074 | 0.1011 | -0.7568 | 1.0877 | |
| MDA-MB-157 | TNBC | Basal B | Etoposide | TOP2 | TOP | 333 | uM | 7498.074 | 0.0827 | -0.7977 | 1.0877 | |
| MDA-MB-175-VII | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.000853 | uM | 7499.074 | 1.0143 | 1.0395 | 0.7239 | |
| MDA-MB-175-VII | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.00427 | uM | 7499.074 | 1.0377 | 1.1049 | 0.7239 | |
| MDA-MB-175-VII | HR+ | Luminal | Etoposide | TOP2 | TOP | 0.0213 | uM | 7499.074 | 1.0105 | 1.0290 | 0.7239 |