Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.000218 | uM | 9035.077 | 0.9952 | 0.9960 | 2.3909 | |
| AU565 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.00109 | uM | 9035.077 | 1.0788 | 1.0645 | 2.3909 | |
| AU565 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.00546 | uM | 9035.077 | 0.9802 | 0.9833 | 2.3909 | |
| AU565 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.0273 | uM | 9035.077 | 1.0986 | 1.0802 | 2.3909 | |
| AU565 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.136 | uM | 9035.077 | 0.9752 | 0.9791 | 2.3909 | |
| AU565 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.682 | uM | 9035.077 | 0.9931 | 0.9943 | 2.3909 | |
| AU565 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 3.41 | uM | 9035.077 | 0.5940 | 0.6085 | 2.3909 | |
| AU565 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 17.1 | uM | 9035.077 | 0.1986 | 0.0172 | 2.3909 | |
| AU565 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 85.2 | uM | 9035.077 | 0.1170 | -0.1848 | 2.3909 | |
| AU565 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.000218 | uM | 9146.121 | 1.0009 | 1.0016 | 1.1366 | |
| AU565 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.00109 | uM | 9146.121 | 1.0770 | 1.1349 | 1.1366 | |
| AU565 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.00546 | uM | 9146.121 | 1.0317 | 1.0557 | 1.1366 | |
| AU565 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.0273 | uM | 9146.121 | 1.0047 | 1.0083 | 1.1366 | |
| AU565 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.136 | uM | 9146.121 | 1.0374 | 1.0658 | 1.1366 | |
| AU565 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.682 | uM | 9146.121 | 0.8986 | 0.8204 | 1.1366 | |
| AU565 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 3.41 | uM | 9146.121 | 0.4009 | -0.1052 | 1.1366 | |
| AU565 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 17.1 | uM | 9146.121 | 0.1927 | -0.5303 | 1.1366 | |
| AU565 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 85.2 | uM | 9146.121 | 0.1477 | -0.6284 | 1.1366 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.000218 | uM | 7798.077 | 1.0351 | 1.0486 | 1.4371 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.00109 | uM | 7798.077 | 1.0817 | 1.1124 | 1.4371 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.00546 | uM | 7798.077 | 1.0044 | 1.0062 | 1.4371 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.0273 | uM | 7798.077 | 1.0374 | 1.0518 | 1.4371 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.136 | uM | 7798.077 | 1.0325 | 1.0450 | 1.4371 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 0.682 | uM | 7798.077 | 1.0128 | 1.0177 | 1.4371 | |
| BT-474 | HER2amp | Luminal | CPT-11 | TOP1 | TOP | 3.41 | uM | 7798.077 | 1.0133 | 1.0185 | 1.4371 |