Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7430.073 | 0.9475 | 0.9459 | 1.9673 | |
| HCC1143 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7430.073 | 1.0001 | 1.0001 | 1.9673 | |
| HCC1143 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7430.073 | 0.9735 | 0.9728 | 1.9673 | |
| HCC1143 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7430.073 | 1.0171 | 1.0173 | 1.9673 | |
| HCC1143 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7430.073 | 0.9616 | 0.9606 | 1.9673 | |
| HCC1143 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7430.073 | 0.9372 | 0.9352 | 1.9673 | |
| HCC1143 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7430.073 | 0.7483 | 0.7259 | 1.9673 | |
| HCC1143 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7430.073 | 0.5452 | 0.4694 | 1.9673 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7431.072 | 1.0425 | 1.0587 | 1.4372 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7431.072 | 1.0406 | 1.0562 | 1.4372 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7431.072 | 0.9968 | 0.9956 | 1.4372 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7431.072 | 1.0342 | 1.0474 | 1.4372 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7431.072 | 0.9309 | 0.9028 | 1.4372 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7431.072 | 0.8809 | 0.8311 | 1.4372 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7431.072 | 0.8457 | 0.7798 | 1.4372 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7431.072 | 0.6345 | 0.4573 | 1.4372 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7431.072 | 0.6604 | 0.4984 | 1.4372 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10518.072 | 1.0558 | 1.0914 | 1.2152 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10518.072 | 0.9323 | 0.8878 | 1.2152 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10518.072 | 0.9374 | 0.8964 | 1.2152 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10518.072 | 0.9955 | 0.9926 | 1.2152 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10518.072 | 0.9185 | 0.8648 | 1.2152 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10518.072 | 0.8050 | 0.6731 | 1.2152 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10518.072 | 0.7928 | 0.6521 | 1.2152 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10518.072 | 0.4990 | 0.1287 | 1.2152 |