Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7490.074 | 0.0179 | -0.5514 | 2.6912 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14912.203 | 0.9180 | 0.9235 | 2.1925 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14912.203 | 0.9180 | 0.9235 | 2.1925 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14912.203 | 0.8461 | 0.8532 | 2.1925 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14912.203 | 0.8461 | 0.8532 | 2.1925 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14912.203 | 0.9518 | 0.9554 | 2.1925 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14912.203 | 0.9518 | 0.9554 | 2.1925 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14912.203 | 0.9106 | 0.9164 | 2.1925 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14912.203 | 0.9106 | 0.9164 | 2.1925 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14912.203 | 0.7016 | 0.7015 | 2.1925 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14912.203 | 0.7016 | 0.7015 | 2.1925 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14912.203 | 0.5456 | 0.5172 | 2.1925 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14912.203 | 0.5456 | 0.5172 | 2.1925 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14912.203 | 0.2262 | 0.0154 | 2.1925 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14912.203 | 0.2262 | 0.0154 | 2.1925 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14912.203 | 0.0191 | -0.6710 | 2.1925 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14912.203 | 0.0191 | -0.6710 | 2.1925 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14912.203 | 0.0144 | -0.7111 | 2.1925 | |
| MCF12A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14912.203 | 0.0144 | -0.7111 | 2.1925 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7492.074 | 1.0286 | 1.0401 | 1.4222 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7492.074 | 1.0286 | 1.0401 | 1.4222 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7492.074 | 1.0306 | 1.0428 | 1.4222 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7492.074 | 1.0306 | 1.0428 | 1.4222 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7492.074 | 1.0634 | 1.0883 | 1.4222 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7492.074 | 1.0634 | 1.0883 | 1.4222 |