Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10518.072 | 0.2025 | -0.4627 | 1.2152 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10753.072 | 0.9964 | 0.9946 | 1.3367 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10753.072 | 0.9555 | 0.9330 | 1.3367 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10753.072 | 0.9824 | 0.9736 | 1.3367 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10753.072 | 0.9575 | 0.9360 | 1.3367 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10753.072 | 0.9611 | 0.9415 | 1.3367 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10753.072 | 0.8526 | 0.7752 | 1.3367 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10753.072 | 0.8255 | 0.7327 | 1.3367 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10753.072 | 0.4500 | 0.1005 | 1.3367 | |
| HCC1187 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10753.072 | 0.1036 | -0.6332 | 1.3367 | |
| HCC1395 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7435.073 | 1.0805 | 1.2287 | 0.7153 | |
| HCC1395 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7435.073 | 0.9534 | 0.8710 | 0.7153 | |
| HCC1395 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7435.073 | 1.0460 | 1.1299 | 0.7153 | |
| HCC1395 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7435.073 | 1.0198 | 1.0556 | 0.7153 | |
| HCC1395 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7435.073 | 1.0512 | 1.1445 | 0.7153 | |
| HCC1395 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7435.073 | 1.0035 | 1.0097 | 0.7153 | |
| HCC1395 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7435.073 | 0.9571 | 0.8810 | 0.7153 | |
| HCC1395 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7435.073 | 0.7115 | 0.2427 | 0.7153 | |
| HCC1395 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7435.073 | 0.5296 | -0.1776 | 0.7153 | |
| HCC1395 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7436.073 | 0.9798 | 0.9671 | 1.2318 | |
| HCC1395 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7436.073 | 0.9442 | 0.9090 | 1.2318 | |
| HCC1395 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7436.073 | 0.9834 | 0.9731 | 1.2318 | |
| HCC1395 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7436.073 | 0.9852 | 0.9759 | 1.2318 | |
| HCC1395 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7436.073 | 0.9749 | 0.9591 | 1.2318 | |
| HCC1395 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7436.073 | 0.9497 | 0.9179 | 1.2318 |