Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM229PE | TNBC | - | AS-252424 | PI3K | PI3K | 0.000853 | uM | 11058.158 | 0.8975 | 0.8997 | 2.1018 | |
| SUM229PE | TNBC | - | AS-252424 | PI3K | PI3K | 0.00427 | uM | 11058.158 | 0.9679 | 0.9692 | 2.1018 | |
| SUM229PE | TNBC | - | AS-252424 | PI3K | PI3K | 0.0213 | uM | 11058.158 | 0.9439 | 0.9458 | 2.1018 | |
| SUM229PE | TNBC | - | AS-252424 | PI3K | PI3K | 0.107 | uM | 11058.158 | 0.9267 | 0.9288 | 2.1018 | |
| SUM229PE | TNBC | - | AS-252424 | PI3K | PI3K | 0.533 | uM | 11058.158 | 0.9200 | 0.9222 | 2.1018 | |
| SUM229PE | TNBC | - | AS-252424 | PI3K | PI3K | 2.67 | uM | 11058.158 | 0.7403 | 0.7333 | 2.1018 | |
| SUM229PE | TNBC | - | AS-252424 | PI3K | PI3K | 13.3 | uM | 11058.158 | 0.5159 | 0.4597 | 2.1018 | |
| SUM229PE | TNBC | - | AS-252424 | PI3K | PI3K | 66.7 | uM | 11058.158 | 0.7647 | 0.7603 | 2.1018 | |
| SUM52PE | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.0000853 | uM | 10695.153 | 1.0492 | 1.0696 | 1.4050 | |
| SUM52PE | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.000427 | uM | 10695.153 | 0.9582 | 0.9401 | 1.4050 | |
| SUM52PE | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.00213 | uM | 10695.153 | 0.9360 | 0.9081 | 1.4050 | |
| SUM52PE | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.0107 | uM | 10695.153 | 0.9057 | 0.8638 | 1.4050 | |
| SUM52PE | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.0533 | uM | 10695.153 | 1.0210 | 1.0297 | 1.4050 | |
| SUM52PE | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.267 | uM | 10695.153 | 0.9144 | 0.8767 | 1.4050 | |
| SUM52PE | HR+ | Luminal | AS-252424 | PI3K | PI3K | 1.33 | uM | 10695.153 | 1.0102 | 1.0144 | 1.4050 | |
| SUM52PE | HR+ | Luminal | AS-252424 | PI3K | PI3K | 6.67 | uM | 10695.153 | 0.6168 | 0.4179 | 1.4050 | |
| SUM52PE | HR+ | Luminal | AS-252424 | PI3K | PI3K | 33.3 | uM | 10695.153 | 0.4356 | 0.1070 | 1.4050 | |
| SUM52PE | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.000171 | uM | 11852.158 | 1.0016 | 1.0024 | 1.3172 | |
| SUM52PE | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.000853 | uM | 11852.158 | 1.0628 | 1.0946 | 1.3172 | |
| SUM52PE | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.00427 | uM | 11852.158 | 1.0344 | 1.0520 | 1.3172 | |
| SUM52PE | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.0213 | uM | 11852.158 | 1.0817 | 1.1228 | 1.3172 | |
| SUM52PE | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.107 | uM | 11852.158 | 1.0523 | 1.0789 | 1.3172 | |
| SUM52PE | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.533 | uM | 11852.158 | 1.0079 | 1.0120 | 1.3172 | |
| SUM52PE | HR+ | Luminal | AS-252424 | PI3K | PI3K | 2.67 | uM | 11852.158 | 0.8639 | 0.7898 | 1.3172 | |
| SUM52PE | HR+ | Luminal | AS-252424 | PI3K | PI3K | 13.3 | uM | 11852.158 | 0.7908 | 0.6736 | 1.3172 |