Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7492.074 | 0.9066 | 0.8667 | 1.4222 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7492.074 | 0.9066 | 0.8667 | 1.4222 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7492.074 | 0.3551 | -0.0342 | 1.4222 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7492.074 | 0.3551 | -0.0342 | 1.4222 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7492.074 | 0.3153 | -0.1117 | 1.4222 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7492.074 | 0.3153 | -0.1117 | 1.4222 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7492.074 | 0.2198 | -0.3106 | 1.4222 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7492.074 | 0.2198 | -0.3106 | 1.4222 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7492.074 | 0.0650 | -0.7074 | 1.4222 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7492.074 | 0.0650 | -0.7074 | 1.4222 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7492.074 | 0.0486 | -0.7615 | 1.4222 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7492.074 | 0.0486 | -0.7615 | 1.4222 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7493.074 | 0.9890 | 0.9809 | 1.1549 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7493.074 | 0.9890 | 0.9809 | 1.1549 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7493.074 | 0.9520 | 0.9166 | 1.1549 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7493.074 | 0.9520 | 0.9166 | 1.1549 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7493.074 | 0.9546 | 0.9211 | 1.1549 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7493.074 | 0.9546 | 0.9211 | 1.1549 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7493.074 | 0.8289 | 0.7001 | 1.1549 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7493.074 | 0.8289 | 0.7001 | 1.1549 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7493.074 | 0.3614 | -0.1716 | 1.1549 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7493.074 | 0.3614 | -0.1716 | 1.1549 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7493.074 | 0.3081 | -0.2784 | 1.1549 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7493.074 | 0.3081 | -0.2784 | 1.1549 | |
| MCF7 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7493.074 | 0.2573 | -0.3827 | 1.1549 |