Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7436.073 | 0.9138 | 0.8589 | 1.2318 | |
| HCC1395 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7436.073 | 0.5776 | 0.2809 | 1.2318 | |
| HCC1395 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7436.073 | 0.5802 | 0.2856 | 1.2318 | |
| HCC1419 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7437.073 | 1.0289 | 1.1273 | 0.4617 | |
| HCC1419 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7437.073 | 1.0353 | 1.1561 | 0.4617 | |
| HCC1419 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7437.073 | 0.9816 | 0.9210 | 0.4617 | |
| HCC1419 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7437.073 | 1.0560 | 1.2506 | 0.4617 | |
| HCC1419 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7437.073 | 1.0091 | 1.0396 | 0.4617 | |
| HCC1419 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7437.073 | 0.9973 | 0.9883 | 0.4617 | |
| HCC1419 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7437.073 | 1.0234 | 1.1029 | 0.4617 | |
| HCC1419 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7437.073 | 1.0113 | 1.0494 | 0.4617 | |
| HCC1419 | HER2amp | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7437.073 | 0.8083 | 0.2612 | 0.4617 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7442.072 | 0.9975 | 0.9934 | 0.7431 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7442.072 | 0.9668 | 0.9113 | 0.7431 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7442.072 | 0.9689 | 0.9167 | 0.7431 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7442.072 | 0.9587 | 0.8897 | 0.7431 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7442.072 | 0.9620 | 0.8985 | 0.7431 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7442.072 | 0.9388 | 0.8371 | 0.7431 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7442.072 | 0.9420 | 0.8454 | 0.7431 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7442.072 | 0.7203 | 0.2860 | 0.7431 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7442.072 | 0.3726 | -0.4703 | 0.7431 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10441.072 | 0.9808 | 0.9681 | 1.2037 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10441.072 | 0.9116 | 0.8520 | 1.2037 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10441.072 | 0.9774 | 0.9624 | 1.2037 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10441.072 | 0.9752 | 0.9587 | 1.2037 |