Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10441.072 | 0.9255 | 0.8755 | 1.2037 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10441.072 | 0.9110 | 0.8509 | 1.2037 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10441.072 | 0.9498 | 0.9162 | 1.2037 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10441.072 | 0.8148 | 0.6870 | 1.2037 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10441.072 | 0.2004 | -0.4739 | 1.2037 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10693.072 | 0.9591 | 0.9020 | 0.8304 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10693.072 | 0.9335 | 0.8410 | 0.8304 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10693.072 | 0.9276 | 0.8269 | 0.8304 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10693.072 | 0.9239 | 0.8181 | 0.8304 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10693.072 | 0.9792 | 0.9500 | 0.8304 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10693.072 | 0.9227 | 0.8154 | 0.8304 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10693.072 | 1.0045 | 1.0108 | 0.8304 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10693.072 | 0.8752 | 0.7033 | 0.8304 | |
| HCC1428 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10693.072 | 0.5883 | 0.0558 | 0.8304 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7449.073 | 1.0067 | 1.0065 | 2.0567 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7449.073 | 0.9441 | 0.9448 | 2.0567 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7449.073 | 0.9087 | 0.9091 | 2.0567 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7449.073 | 0.9320 | 0.9327 | 2.0567 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7449.073 | 0.9566 | 0.9573 | 2.0567 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7449.073 | 0.8984 | 0.8985 | 2.0567 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7449.073 | 0.9583 | 0.9590 | 2.0567 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7449.073 | 0.8926 | 0.8925 | 2.0567 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7449.073 | 0.4076 | 0.2928 | 2.0567 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10442.072 | 1.0061 | 1.0069 | 1.7484 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10442.072 | 0.9839 | 0.9815 | 1.7484 |