Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10442.072 | 0.9738 | 0.9698 | 1.7484 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10442.072 | 0.9345 | 0.9240 | 1.7484 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10442.072 | 0.9998 | 0.9997 | 1.7484 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10442.072 | 0.9228 | 0.9102 | 1.7484 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10442.072 | 0.9665 | 0.9614 | 1.7484 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10442.072 | 0.7143 | 0.6499 | 1.7484 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10442.072 | 0.2114 | -0.1777 | 1.7484 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10872.072 | 0.9793 | 0.9737 | 1.5765 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10872.072 | 1.0058 | 1.0073 | 1.5765 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10872.072 | 0.9920 | 0.9898 | 1.5765 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10872.072 | 1.0484 | 1.0609 | 1.5765 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10872.072 | 0.9617 | 0.9511 | 1.5765 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10872.072 | 0.9964 | 0.9955 | 1.5765 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10872.072 | 0.9037 | 0.8756 | 1.5765 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10872.072 | 1.0307 | 1.0388 | 1.5765 | |
| HCC1569 | HER2amp | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10872.072 | 0.4799 | 0.2554 | 1.5765 | |
| HCC1806 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7451.073 | 1.0146 | 1.0136 | 2.1268 | |
| HCC1806 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 7451.073 | 0.9626 | 0.9645 | 2.1268 | |
| HCC1806 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 7451.073 | 0.9487 | 0.9511 | 2.1268 | |
| HCC1806 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 7451.073 | 0.9868 | 0.9875 | 2.1268 | |
| HCC1806 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 7451.073 | 0.9828 | 0.9838 | 2.1268 | |
| HCC1806 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 7451.073 | 0.9350 | 0.9378 | 2.1268 | |
| HCC1806 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 7451.073 | 0.9495 | 0.9519 | 2.1268 | |
| HCC1806 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 7451.073 | 0.6360 | 0.6167 | 2.1268 | |
| HCC1806 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 7451.073 | 0.4450 | 0.3667 | 2.1268 |