Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 2.67 | uM | 10580.141 | 0.9233 | 0.7969 | 0.7451 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 13.3 | uM | 10580.141 | 0.8590 | 0.6310 | 0.7451 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 66.7 | uM | 10580.141 | 0.8886 | 0.7068 | 0.7451 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 0.0000853 | uM | 10754.153 | 0.9919 | 0.9874 | 1.2774 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 0.000427 | uM | 10754.153 | 0.9807 | 0.9698 | 1.2774 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 0.00213 | uM | 10754.153 | 0.9606 | 0.9380 | 1.2774 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 0.0107 | uM | 10754.153 | 0.9758 | 0.9620 | 1.2774 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 0.0533 | uM | 10754.153 | 1.0331 | 1.0517 | 1.2774 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 0.267 | uM | 10754.153 | 0.9624 | 0.9408 | 1.2774 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 1.33 | uM | 10754.153 | 1.0385 | 1.0601 | 1.2774 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 6.67 | uM | 10754.153 | 0.8244 | 0.7194 | 1.2774 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 33.3 | uM | 10754.153 | 0.5297 | 0.2161 | 1.2774 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 0.000171 | uM | 11938.158 | 0.9521 | 0.8388 | 0.5846 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 0.000853 | uM | 11938.158 | 0.8884 | 0.6335 | 0.5846 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 0.00427 | uM | 11938.158 | 0.9911 | 0.9697 | 0.5846 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 0.0213 | uM | 11938.158 | 0.9548 | 0.8480 | 0.5846 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 0.107 | uM | 11938.158 | 0.9333 | 0.7774 | 0.5846 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 0.533 | uM | 11938.158 | 0.9365 | 0.7877 | 0.5846 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 2.67 | uM | 11938.158 | 0.9009 | 0.6729 | 0.5846 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 13.3 | uM | 11938.158 | 0.8319 | 0.4597 | 0.5846 | |
| UACC-812 | HER2amp | Luminal | AS-252424 | PI3K | PI3K | 66.7 | uM | 11938.158 | 0.7033 | 0.0953 | 0.5846 | |
| ZR-75-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.0000853 | uM | 11660.153 | 0.9598 | 0.9024 | 0.8197 | |
| ZR-75-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.000427 | uM | 11660.153 | 0.8688 | 0.6847 | 0.8197 | |
| ZR-75-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.00213 | uM | 11660.153 | 0.9890 | 0.9733 | 0.8197 | |
| ZR-75-1 | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.0107 | uM | 11660.153 | 0.9278 | 0.8253 | 0.8197 |