Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 5909.072 | 0.9937 | 0.9957 | 2.9441 | |
| BT-549 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 5909.072 | 0.9856 | 0.9902 | 2.9441 | |
| BT-549 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 5909.072 | 0.9771 | 0.9843 | 2.9441 | |
| BT-549 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 5909.072 | 0.9107 | 0.9374 | 2.9441 | |
| BT-549 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 5909.072 | 0.3878 | 0.4498 | 2.9441 | |
| BT-549 | TNBC | Basal B | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 5909.072 | 0.2056 | 0.1687 | 2.9441 | |
| CAMA-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10473.072 | 1.0106 | 1.0163 | 1.2996 | |
| CAMA-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10473.072 | 0.8812 | 0.8145 | 1.2996 | |
| CAMA-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10473.072 | 0.9087 | 0.8580 | 1.2996 | |
| CAMA-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10473.072 | 0.9991 | 0.9987 | 1.2996 | |
| CAMA-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10473.072 | 1.0062 | 1.0096 | 1.2996 | |
| CAMA-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10473.072 | 0.9655 | 0.9466 | 1.2996 | |
| CAMA-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10473.072 | 0.9743 | 0.9603 | 1.2996 | |
| CAMA-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10473.072 | 0.9234 | 0.8810 | 1.2996 | |
| CAMA-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10473.072 | 0.3161 | -0.1755 | 1.2996 | |
| CAMA-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 10755.072 | 0.9703 | 0.9190 | 0.7300 | |
| CAMA-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.00213 | uM | 10755.072 | 0.8717 | 0.6572 | 0.7300 | |
| CAMA-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0107 | uM | 10755.072 | 0.9698 | 0.9178 | 0.7300 | |
| CAMA-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.0533 | uM | 10755.072 | 0.9240 | 0.7947 | 0.7300 | |
| CAMA-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 0.267 | uM | 10755.072 | 0.9473 | 0.8570 | 0.7300 | |
| CAMA-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 1.33 | uM | 10755.072 | 0.9234 | 0.7931 | 0.7300 | |
| CAMA-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 6.67 | uM | 10755.072 | 0.9758 | 0.9340 | 0.7300 | |
| CAMA-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 33.3 | uM | 10755.072 | 0.8352 | 0.5629 | 0.7300 | |
| CAMA-1 | HR+ | Luminal | Baicalein | Lipoxygenase | Metabolism | 167 | uM | 10755.072 | 0.7213 | 0.2784 | 0.7300 | |
| HCC1143 | TNBC | Basal A | Baicalein | Lipoxygenase | Metabolism | 0.000427 | uM | 7430.073 | 1.0503 | 1.0506 | 1.9673 |