Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.107 | uM | 7437.093 | 1.0645 | 1.2823 | 0.4731 | |
| HCC1419 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.533 | uM | 7437.093 | 0.9608 | 0.8380 | 0.4731 | |
| HCC1419 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 2.67 | uM | 7437.093 | 1.0000 | 0.9998 | 0.4731 | |
| HCC1419 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 13.3 | uM | 7437.093 | 0.9343 | 0.7322 | 0.4731 | |
| HCC1419 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 66.7 | uM | 7437.093 | 0.9253 | 0.6973 | 0.4731 | |
| HCC1428 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.000341 | uM | 7442.1 | 1.0133 | 1.0304 | 0.8780 | |
| HCC1428 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.00171 | uM | 7442.1 | 0.9557 | 0.8994 | 0.8780 | |
| HCC1428 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.00853 | uM | 7442.1 | 0.9451 | 0.8755 | 0.8780 | |
| HCC1428 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.0427 | uM | 7442.1 | 0.9786 | 0.9513 | 0.8780 | |
| HCC1428 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.213 | uM | 7442.1 | 0.9945 | 0.9875 | 0.8780 | |
| HCC1428 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 1.07 | uM | 7442.1 | 0.9209 | 0.8207 | 0.8780 | |
| HCC1428 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 5.33 | uM | 7442.1 | 0.6922 | 0.3155 | 0.8780 | |
| HCC1428 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 26.7 | uM | 7442.1 | 0.8163 | 0.5872 | 0.8780 | |
| HCC1428 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 133 | uM | 7442.1 | 0.6698 | 0.2671 | 0.8780 | |
| HCC1428 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.000171 | uM | 10441.093 | 0.9658 | 0.9401 | 1.1458 | |
| HCC1428 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.000853 | uM | 10441.093 | 0.9698 | 0.9471 | 1.1458 | |
| HCC1428 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.00427 | uM | 10441.093 | 0.9485 | 0.9098 | 1.1458 | |
| HCC1428 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.0213 | uM | 10441.093 | 1.0073 | 1.0127 | 1.1458 | |
| HCC1428 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.107 | uM | 10441.093 | 1.0031 | 1.0055 | 1.1458 | |
| HCC1428 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.533 | uM | 10441.093 | 0.8993 | 0.8230 | 1.1458 | |
| HCC1428 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 2.67 | uM | 10441.093 | 0.7221 | 0.5053 | 1.1458 | |
| HCC1428 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 13.3 | uM | 10441.093 | 0.6974 | 0.4603 | 1.1458 | |
| HCC1428 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 66.7 | uM | 10441.093 | 0.5395 | 0.1672 | 1.1458 | |
| HCC1569 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.000171 | uM | 10442.093 | 0.9482 | 0.9379 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.000853 | uM | 10442.093 | 1.0142 | 1.0168 | 1.6861 |