Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.00427 | uM | 10442.093 | 0.9704 | 0.9647 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.0213 | uM | 10442.093 | 0.9778 | 0.9735 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.107 | uM | 10442.093 | 1.0266 | 1.0313 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.533 | uM | 10442.093 | 0.8943 | 0.8718 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 2.67 | uM | 10442.093 | 0.6808 | 0.5922 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 13.3 | uM | 10442.093 | 0.4019 | 0.1648 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 66.7 | uM | 10442.093 | 0.3262 | 0.0292 | 1.6861 | |
| HCC1806 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.000171 | uM | 7451.093 | 0.9375 | 0.9420 | 2.1935 | |
| HCC1806 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.000853 | uM | 7451.093 | 0.9739 | 0.9761 | 2.1935 | |
| HCC1806 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.00427 | uM | 7451.093 | 0.9569 | 0.9603 | 2.1935 | |
| HCC1806 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.0213 | uM | 7451.093 | 0.9562 | 0.9596 | 2.1935 | |
| HCC1806 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.107 | uM | 7451.093 | 0.9731 | 0.9753 | 2.1935 | |
| HCC1806 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.533 | uM | 7451.093 | 0.9450 | 0.9491 | 2.1935 | |
| HCC1806 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 2.67 | uM | 7451.093 | 0.7402 | 0.7437 | 2.1935 | |
| HCC1806 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 13.3 | uM | 7451.093 | 0.5545 | 0.5285 | 2.1935 | |
| HCC1806 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 66.7 | uM | 7451.093 | 0.5465 | 0.5184 | 2.1935 | |
| HCC1937 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.000171 | uM | 7453.093 | 1.0035 | 1.0045 | 1.5872 | |
| HCC1937 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.000853 | uM | 7453.093 | 1.0469 | 1.0586 | 1.5872 | |
| HCC1937 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.00427 | uM | 7453.093 | 1.0462 | 1.0577 | 1.5872 | |
| HCC1937 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.0213 | uM | 7453.093 | 1.0236 | 1.0296 | 1.5872 | |
| HCC1937 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.107 | uM | 7453.093 | 1.1134 | 1.1400 | 1.5872 | |
| HCC1937 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.533 | uM | 7453.093 | 0.9476 | 0.9333 | 1.5872 | |
| HCC1937 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 2.67 | uM | 7453.093 | 0.9615 | 0.9511 | 1.5872 | |
| HCC1937 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 13.3 | uM | 7453.093 | 0.6559 | 0.5333 | 1.5872 | |
| HCC1937 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 66.7 | uM | 7453.093 | 0.7413 | 0.6563 | 1.5872 |