Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.000171 | uM | 7454.093 | 0.8216 | 0.7261 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.000853 | uM | 7454.093 | 0.8500 | 0.7707 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.00427 | uM | 7454.093 | 0.9003 | 0.8487 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.0213 | uM | 7454.093 | 0.9208 | 0.8800 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.107 | uM | 7454.093 | 0.8836 | 0.8229 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.533 | uM | 7454.093 | 0.8166 | 0.7183 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 2.67 | uM | 7454.093 | 0.7949 | 0.6840 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 13.3 | uM | 7454.093 | 0.8476 | 0.7670 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 66.7 | uM | 7454.093 | 0.9293 | 0.8930 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.000171 | uM | 7455.093 | 1.0006 | 1.0007 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.000853 | uM | 7455.093 | 0.9832 | 0.9804 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.00427 | uM | 7455.093 | 1.0200 | 1.0231 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.0213 | uM | 7455.093 | 1.0631 | 1.0722 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.107 | uM | 7455.093 | 1.0357 | 1.0410 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.533 | uM | 7455.093 | 0.9258 | 0.9126 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 2.67 | uM | 7455.093 | 0.7985 | 0.7554 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 13.3 | uM | 7455.093 | 0.6433 | 0.5488 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 66.7 | uM | 7455.093 | 0.5467 | 0.4095 | 1.7255 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.000341 | uM | 10469.1 | 0.9518 | 0.9382 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.00171 | uM | 10469.1 | 1.0280 | 1.0355 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.00853 | uM | 10469.1 | 0.9662 | 0.9567 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.0427 | uM | 10469.1 | 1.0295 | 1.0373 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 0.213 | uM | 10469.1 | 1.0230 | 1.0292 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 1.07 | uM | 10469.1 | 0.8827 | 0.8473 | 1.5717 | |
| HCC1954 | HER2amp | Basal A | TPCA-1 | IKK | NFKB | 5.33 | uM | 10469.1 | 0.7557 | 0.6735 | 1.5717 |