Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 5.33 | uM | 7431.1 | 0.5230 | 0.3198 | 1.5594 | |
| HCC1187 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 26.7 | uM | 7431.1 | 0.3688 | 0.0550 | 1.5594 | |
| HCC1187 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 133 | uM | 7431.1 | 0.1812 | -0.3311 | 1.5594 | |
| HCC1187 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.000341 | uM | 10518.1 | 0.9622 | 0.9460 | 1.4056 | |
| HCC1187 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.00171 | uM | 10518.1 | 0.9281 | 0.8967 | 1.4056 | |
| HCC1187 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.00853 | uM | 10518.1 | 0.9077 | 0.8669 | 1.4056 | |
| HCC1187 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.0427 | uM | 10518.1 | 0.9145 | 0.8768 | 1.4056 | |
| HCC1187 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.213 | uM | 10518.1 | 0.8736 | 0.8167 | 1.4056 | |
| HCC1187 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 1.07 | uM | 10518.1 | 0.7692 | 0.6594 | 1.4056 | |
| HCC1187 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 5.33 | uM | 10518.1 | 0.5213 | 0.2583 | 1.4056 | |
| HCC1187 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 26.7 | uM | 10518.1 | 0.3313 | -0.0887 | 1.4056 | |
| HCC1187 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 133 | uM | 10518.1 | 0.2784 | -0.1947 | 1.4056 | |
| HCC1395 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.000171 | uM | 7436.093 | 0.9802 | 0.9685 | 1.2596 | |
| HCC1395 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.000853 | uM | 7436.093 | 1.0260 | 1.0411 | 1.2596 | |
| HCC1395 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.00427 | uM | 7436.093 | 1.0160 | 1.0253 | 1.2596 | |
| HCC1395 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.0213 | uM | 7436.093 | 1.0398 | 1.0629 | 1.2596 | |
| HCC1395 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.107 | uM | 7436.093 | 1.0515 | 1.0813 | 1.2596 | |
| HCC1395 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.533 | uM | 7436.093 | 1.0143 | 1.0226 | 1.2596 | |
| HCC1395 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 2.67 | uM | 7436.093 | 0.8874 | 0.8191 | 1.2596 | |
| HCC1395 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 13.3 | uM | 7436.093 | 0.4622 | 0.0838 | 1.2596 | |
| HCC1395 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 66.7 | uM | 7436.093 | 0.3305 | -0.1695 | 1.2596 | |
| HCC1419 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.000171 | uM | 7437.093 | 0.9929 | 0.9700 | 0.4731 | |
| HCC1419 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.000853 | uM | 7437.093 | 0.9715 | 0.8815 | 0.4731 | |
| HCC1419 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.00427 | uM | 7437.093 | 1.0171 | 1.0729 | 0.4731 | |
| HCC1419 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.0213 | uM | 7437.093 | 0.9911 | 0.9626 | 0.4731 |