Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 66.7 | uM | 5909.093 | 0.6456 | 0.7181 | 2.8805 | |
| CAMA-1 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.000341 | uM | 10473.1 | 0.9218 | 0.8842 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.00171 | uM | 10473.1 | 0.8527 | 0.7796 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.00853 | uM | 10473.1 | 0.8140 | 0.7202 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.0427 | uM | 10473.1 | 0.9431 | 0.9160 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.213 | uM | 10473.1 | 0.8977 | 0.8480 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 1.07 | uM | 10473.1 | 0.9247 | 0.8886 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 5.33 | uM | 10473.1 | 0.8631 | 0.7955 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 26.7 | uM | 10473.1 | 0.8624 | 0.7945 | 1.3652 | |
| CAMA-1 | HR+ | Luminal | TPCA-1 | IKK | NFKB | 133 | uM | 10473.1 | 0.8575 | 0.7870 | 1.3652 | |
| HCC1143 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.000171 | uM | 7430.093 | 0.9469 | 0.9446 | 1.9432 | |
| HCC1143 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.000853 | uM | 7430.093 | 1.0280 | 1.0286 | 1.9432 | |
| HCC1143 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.00427 | uM | 7430.093 | 0.9701 | 0.9690 | 1.9432 | |
| HCC1143 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.0213 | uM | 7430.093 | 0.9690 | 0.9678 | 1.9432 | |
| HCC1143 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.107 | uM | 7430.093 | 0.9933 | 0.9931 | 1.9432 | |
| HCC1143 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.533 | uM | 7430.093 | 0.9428 | 0.9403 | 1.9432 | |
| HCC1143 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 2.67 | uM | 7430.093 | 0.8935 | 0.8874 | 1.9432 | |
| HCC1143 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 13.3 | uM | 7430.093 | 0.5504 | 0.4709 | 1.9432 | |
| HCC1143 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 66.7 | uM | 7430.093 | 0.5399 | 0.4563 | 1.9432 | |
| HCC1187 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.000341 | uM | 7431.1 | 0.9701 | 0.9614 | 1.5594 | |
| HCC1187 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.00171 | uM | 7431.1 | 0.9454 | 0.9293 | 1.5594 | |
| HCC1187 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.00853 | uM | 7431.1 | 0.9569 | 0.9443 | 1.5594 | |
| HCC1187 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.0427 | uM | 7431.1 | 0.9278 | 0.9062 | 1.5594 | |
| HCC1187 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.213 | uM | 7431.1 | 0.8841 | 0.8481 | 1.5594 | |
| HCC1187 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 1.07 | uM | 7431.1 | 0.7850 | 0.7125 | 1.5594 |