Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Taxol | TUBB | TUBB | 6.67 | uM | 13038.002 | 0.4675 | 0.0639 | 1.2045 | |
| HCC1569 | HER2amp | Basal A | Taxol | TUBB | TUBB | 33.3 | uM | 13038.002 | 0.5071 | 0.1382 | 1.2045 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0000853 | uM | 7829.002 | 0.9979 | 0.9978 | 1.8681 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.000427 | uM | 7829.002 | 1.0008 | 1.0008 | 1.8681 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.00213 | uM | 7829.002 | 1.0082 | 1.0088 | 1.8681 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0107 | uM | 7829.002 | 0.2502 | -0.0473 | 1.8681 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0533 | uM | 7829.002 | 0.0866 | -0.4600 | 1.8681 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.267 | uM | 7829.002 | 0.0434 | -0.6272 | 1.8681 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 1.33 | uM | 7829.002 | 0.0416 | -0.6356 | 1.8681 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 6.67 | uM | 7829.002 | 0.0374 | -0.6554 | 1.8681 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 33.3 | uM | 7829.002 | 0.0536 | -0.5826 | 1.8681 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0000853 | uM | 9376.002 | 1.0722 | 1.0948 | 1.5057 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.000427 | uM | 9376.002 | 1.0234 | 1.0310 | 1.5057 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.00213 | uM | 9376.002 | 0.9914 | 0.9886 | 1.5057 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0107 | uM | 9376.002 | 0.4847 | 0.2363 | 1.5057 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0533 | uM | 9376.002 | 0.2132 | -0.2835 | 1.5057 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.267 | uM | 9376.002 | 0.1646 | -0.3967 | 1.5057 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 1.33 | uM | 9376.002 | 0.1527 | -0.4260 | 1.5057 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 6.67 | uM | 9376.002 | 0.1555 | -0.4190 | 1.5057 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 33.3 | uM | 9376.002 | 0.1151 | -0.5241 | 1.5057 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0000853 | uM | 12702.002 | 1.0189 | 1.0201 | 1.8712 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.000427 | uM | 12702.002 | 1.0035 | 1.0038 | 1.8712 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.00213 | uM | 12702.002 | 0.9100 | 0.9017 | 1.8712 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0107 | uM | 12702.002 | 0.2206 | -0.1083 | 1.8712 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0533 | uM | 12702.002 | 0.0780 | -0.4885 | 1.8712 |