Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 13030.002 | 1.2069 | 1.7765 | 0.5732 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 13030.002 | 1.0310 | 1.1092 | 0.5732 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 13030.002 | 0.7877 | 0.3189 | 0.5732 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 13030.002 | 0.2256 | -0.8511 | 0.5732 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 13030.002 | 0.1872 | -0.8924 | 0.5732 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 13030.002 | 0.2145 | -0.8637 | 0.5732 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 13030.002 | 0.2259 | -0.8508 | 0.5732 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 13030.002 | 0.1954 | -0.8841 | 0.5732 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 13030.002 | 0.1896 | -0.8900 | 0.5732 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9157.002 | 1.0499 | 1.1075 | 0.9306 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9157.002 | 0.9937 | 0.9864 | 0.9306 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9157.002 | 0.9737 | 0.9435 | 0.9306 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9157.002 | 0.7785 | 0.5281 | 0.9306 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9157.002 | 0.5270 | 0.0048 | 0.9306 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9157.002 | 0.4843 | -0.0823 | 0.9306 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9157.002 | 0.4929 | -0.0649 | 0.9306 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9157.002 | 0.4324 | -0.1877 | 0.9306 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9157.002 | 0.4186 | -0.2154 | 0.9306 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9158.002 | 1.0346 | 1.1645 | 0.4298 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9158.002 | 1.0287 | 1.1361 | 0.4298 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9158.002 | 1.1135 | 1.5683 | 0.4298 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9158.002 | 0.8310 | 0.2999 | 0.4298 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9158.002 | 0.4897 | -0.6202 | 0.4298 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9158.002 | 0.4696 | -0.6555 | 0.4298 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9158.002 | 0.4741 | -0.6477 | 0.4298 |