Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9158.002 | 0.3953 | -0.7693 | 0.4298 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9158.002 | 0.3588 | -0.8158 | 0.4298 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9163.002 | 1.0588 | 1.1998 | 0.6004 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9163.002 | 0.9962 | 0.9873 | 0.6004 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9163.002 | 1.0914 | 1.3137 | 0.6004 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9163.002 | 0.7532 | 0.2474 | 0.6004 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9163.002 | 0.3669 | -0.6236 | 0.6004 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9163.002 | 0.3145 | -0.7088 | 0.6004 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9163.002 | 0.3134 | -0.7105 | 0.6004 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9163.002 | 0.2699 | -0.7742 | 0.6004 | |
| BT-474 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9163.002 | 0.2587 | -0.7896 | 0.6004 | |
| BT-483 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 7801.002 | 0.9921 | 0.9621 | 0.4140 | |
| BT-483 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 7801.002 | 0.9461 | 0.7494 | 0.4140 | |
| BT-483 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 7801.002 | 0.9716 | 0.8656 | 0.4140 | |
| BT-483 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 7801.002 | 0.9043 | 0.5685 | 0.4140 | |
| BT-483 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 7801.002 | 0.8517 | 0.3573 | 0.4140 | |
| BT-483 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 7801.002 | 0.7828 | 0.1068 | 0.4140 | |
| BT-483 | HR+ | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 7801.002 | 0.7690 | 0.0603 | 0.4140 | |
| BT-483 | HR+ | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 7801.002 | 0.6895 | -0.1853 | 0.4140 | |
| BT-483 | HR+ | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 7801.002 | 0.5771 | -0.4700 | 0.4140 | |
| BT-483 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9186.002 | 1.0071 | 1.0301 | 0.4768 | |
| BT-483 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9186.002 | 1.0089 | 1.0377 | 0.4768 | |
| BT-483 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9186.002 | 1.0423 | 1.1815 | 0.4768 | |
| BT-483 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9186.002 | 0.8779 | 0.5221 | 0.4768 | |
| BT-483 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9186.002 | 0.8288 | 0.3488 | 0.4768 |