Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
ZR75B	HR+	Luminal	TCS PIM-1 1	Pim kinase	PIM	1.07	uM	11939.135	0.9839	0.9799	1.5987
ZR75B	HR+	Luminal	TCS PIM-1 1	Pim kinase	PIM	5.33	uM	11939.135	0.9585	0.9477	1.5987
ZR75B	HR+	Luminal	TCS PIM-1 1	Pim kinase	PIM	26.7	uM	11939.135	0.8135	0.7578	1.5987
ZR75B	HR+	Luminal	TCS PIM-1 1	Pim kinase	PIM	133	uM	11939.135	0.8046	0.7457	1.5987
184A1	NM	Basal	Temsirolimus	MTOR	MTOR	0.000341	uM	12509.168	1.0159	1.0235	1.3516
184A1	NM	Basal	Temsirolimus	MTOR	MTOR	0.00171	uM	12509.168	1.0126	1.0186	1.3516
184A1	NM	Basal	Temsirolimus	MTOR	MTOR	0.00853	uM	12509.168	0.9265	0.8901	1.3516
184A1	NM	Basal	Temsirolimus	MTOR	MTOR	0.0427	uM	12509.168	0.7351	0.5927	1.3516
184A1	NM	Basal	Temsirolimus	MTOR	MTOR	0.213	uM	12509.168	0.6611	0.4725	1.3516
184A1	NM	Basal	Temsirolimus	MTOR	MTOR	1.07	uM	12509.168	0.6579	0.4672	1.3516
184A1	NM	Basal	Temsirolimus	MTOR	MTOR	5.33	uM	12509.168	0.6145	0.3950	1.3516
184A1	NM	Basal	Temsirolimus	MTOR	MTOR	26.7	uM	12509.168	0.0306	-0.8483	1.3516
184A1	NM	Basal	Temsirolimus	MTOR	MTOR	133	uM	12509.168	0.0119	-0.9247	1.3516
184B5	NM	Basal	Temsirolimus	MTOR	MTOR	0.000341	uM	12566.168	0.9520	0.9327	1.4366
184B5	NM	Basal	Temsirolimus	MTOR	MTOR	0.00171	uM	12566.168	0.9759	0.9663	1.4366
184B5	NM	Basal	Temsirolimus	MTOR	MTOR	0.00853	uM	12566.168	0.8824	0.8331	1.4366
184B5	NM	Basal	Temsirolimus	MTOR	MTOR	0.0427	uM	12566.168	0.8482	0.7835	1.4366
184B5	NM	Basal	Temsirolimus	MTOR	MTOR	0.213	uM	12566.168	0.8089	0.7255	1.4366
184B5	NM	Basal	Temsirolimus	MTOR	MTOR	1.07	uM	12566.168	0.7822	0.6857	1.4366
184B5	NM	Basal	Temsirolimus	MTOR	MTOR	5.33	uM	12566.168	0.7485	0.6347	1.4366
184B5	NM	Basal	Temsirolimus	MTOR	MTOR	26.7	uM	12566.168	0.7730	0.6718	1.4366
184B5	NM	Basal	Temsirolimus	MTOR	MTOR	133	uM	12566.168	0.0114	-0.9110	1.4366
600MPE	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.000341	uM	12224.144	0.9136	0.8305	1.0210
600MPE	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.00171	uM	12224.144	0.8952	0.7944	1.0210
600MPE	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.00853	uM	12224.144	0.9503	0.9025	1.0210

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)