Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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BT-483 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9186.002 | 0.7684 | 0.1510 | 0.4768 | |
BT-483 | HR+ | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9186.002 | 0.8446 | 0.4034 | 0.4768 | |
BT-483 | HR+ | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9186.002 | 0.7188 | 0.0007 | 0.4768 | |
BT-483 | HR+ | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9186.002 | 0.6136 | -0.2821 | 0.4768 | |
BT-549 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0000853 | uM | 10261.002 | 1.1081 | 1.0956 | 2.1983 | |
BT-549 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.000427 | uM | 10261.002 | 0.9926 | 0.9932 | 2.1983 | |
BT-549 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.00213 | uM | 10261.002 | 1.0090 | 1.0082 | 2.1983 | |
BT-549 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0107 | uM | 10261.002 | 0.5030 | 0.4631 | 2.1983 | |
BT-549 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0533 | uM | 10261.002 | 0.3036 | 0.1629 | 2.1983 | |
BT-549 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.267 | uM | 10261.002 | 0.2984 | 0.1537 | 2.1983 | |
BT-549 | TNBC | Basal B | Taxol | TUBB | TUBB | 1.33 | uM | 10261.002 | 0.2745 | 0.1107 | 2.1983 | |
BT-549 | TNBC | Basal B | Taxol | TUBB | TUBB | 6.67 | uM | 10261.002 | 0.2610 | 0.0857 | 2.1983 | |
BT-549 | TNBC | Basal B | Taxol | TUBB | TUBB | 33.3 | uM | 10261.002 | 0.2259 | 0.0166 | 2.1983 | |
BT-549 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0000853 | uM | 12690.002 | 1.0262 | 1.0213 | 2.4397 | |
BT-549 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.000427 | uM | 12690.002 | 0.9807 | 0.9841 | 2.4397 | |
BT-549 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.00213 | uM | 12690.002 | 0.8931 | 0.9095 | 2.4397 | |
BT-549 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0107 | uM | 12690.002 | 0.2921 | 0.2077 | 2.4397 | |
BT-549 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0533 | uM | 12690.002 | 0.2341 | 0.1030 | 2.4397 | |
BT-549 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.267 | uM | 12690.002 | 0.2127 | 0.0604 | 2.4397 | |
BT-549 | TNBC | Basal B | Taxol | TUBB | TUBB | 1.33 | uM | 12690.002 | 0.1659 | -0.0423 | 2.4397 | |
BT-549 | TNBC | Basal B | Taxol | TUBB | TUBB | 6.67 | uM | 12690.002 | 0.1776 | -0.0151 | 2.4397 | |
BT-549 | TNBC | Basal B | Taxol | TUBB | TUBB | 33.3 | uM | 12690.002 | 0.2066 | 0.0478 | 2.4397 | |
CAMA-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9210.002 | 1.0149 | 1.0332 | 0.8958 | |
CAMA-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9210.002 | 1.0027 | 1.0059 | 0.8958 | |
CAMA-1 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9210.002 | 0.9794 | 0.9540 | 0.8958 |