Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9118.002 | 1.0836 | 1.1692 | 0.9880 | |
| 600MPE | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9118.002 | 0.9275 | 0.8533 | 0.9880 | |
| 600MPE | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9118.002 | 0.7839 | 0.5632 | 0.9880 | |
| 600MPE | HR+ | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9118.002 | 0.7009 | 0.3957 | 0.9880 | |
| 600MPE | HR+ | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9118.002 | 0.7042 | 0.4024 | 0.9880 | |
| 600MPE | HR+ | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9118.002 | 0.6989 | 0.3917 | 0.9880 | |
| 600MPE | HR+ | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9118.002 | 0.6989 | 0.3917 | 0.9880 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 7793.002 | 1.0532 | 1.0919 | 1.1545 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 7793.002 | 0.9967 | 0.9942 | 1.1545 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 7793.002 | 0.9964 | 0.9938 | 1.1545 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 7793.002 | 0.4627 | 0.0260 | 1.1545 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 7793.002 | 0.0492 | -0.8529 | 1.1545 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 7793.002 | 0.0472 | -0.8579 | 1.1545 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 7793.002 | 0.0520 | -0.8455 | 1.1545 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 7793.002 | 0.0427 | -0.8698 | 1.1545 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 7793.002 | 0.0364 | -0.8865 | 1.1545 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9146.002 | 1.0731 | 1.1150 | 1.2611 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9146.002 | 0.9550 | 0.9283 | 1.2611 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9146.002 | 1.0186 | 1.0295 | 1.2611 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9146.002 | 0.4188 | 0.0030 | 1.2611 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9146.002 | 0.1054 | -0.6641 | 1.2611 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9146.002 | 0.0868 | -0.7120 | 1.2611 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9146.002 | 0.0946 | -0.6917 | 1.2611 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9146.002 | 0.0912 | -0.7005 | 1.2611 | |
| AU565 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9146.002 | 0.0828 | -0.7227 | 1.2611 |