Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | TAPI-0 | TACE/Collagenase | 0.0533 | uM | 5897.096 | 0.9847 | 0.9760 | 1.2810 | ||
| 184B5 | NM | Basal | TAPI-0 | TACE/Collagenase | 0.267 | uM | 5897.096 | 1.0035 | 1.0054 | 1.2810 | ||
| 184B5 | NM | Basal | TAPI-0 | TACE/Collagenase | 1.33 | uM | 5897.096 | 0.9654 | 0.9458 | 1.2810 | ||
| 184B5 | NM | Basal | TAPI-0 | TACE/Collagenase | 6.67 | uM | 5897.096 | 0.9821 | 0.9720 | 1.2810 | ||
| 184B5 | NM | Basal | TAPI-0 | TACE/Collagenase | 33.3 | uM | 5897.096 | 0.9314 | 0.8920 | 1.2810 | ||
| 600MPE | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 0.0000853 | uM | 5898.096 | 1.0024 | 1.0071 | 0.6718 | ||
| 600MPE | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 0.000427 | uM | 5898.096 | 0.9854 | 0.9568 | 0.6718 | ||
| 600MPE | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 0.00213 | uM | 5898.096 | 0.9883 | 0.9654 | 0.6718 | ||
| 600MPE | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 0.0107 | uM | 5898.096 | 1.0215 | 1.0644 | 0.6718 | ||
| 600MPE | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 0.0533 | uM | 5898.096 | 1.0030 | 1.0088 | 0.6718 | ||
| 600MPE | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 0.267 | uM | 5898.096 | 0.9761 | 0.9293 | 0.6718 | ||
| 600MPE | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 1.33 | uM | 5898.096 | 0.9831 | 0.9498 | 0.6718 | ||
| 600MPE | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 6.67 | uM | 5898.096 | 0.9542 | 0.8652 | 0.6718 | ||
| 600MPE | HR+ | Luminal | TAPI-0 | TACE/Collagenase | 33.3 | uM | 5898.096 | 0.8884 | 0.6770 | 0.6718 | ||
| AU565 | HER2amp | Luminal | TAPI-0 | TACE/Collagenase | 0.0000853 | uM | 5900.096 | 1.0058 | 1.0042 | 2.7795 | ||
| AU565 | HER2amp | Luminal | TAPI-0 | TACE/Collagenase | 0.000427 | uM | 5900.096 | 0.9143 | 0.9366 | 2.7795 | ||
| AU565 | HER2amp | Luminal | TAPI-0 | TACE/Collagenase | 0.00213 | uM | 5900.096 | 0.9703 | 0.9784 | 2.7795 | ||
| AU565 | HER2amp | Luminal | TAPI-0 | TACE/Collagenase | 0.0107 | uM | 5900.096 | 1.0100 | 1.0071 | 2.7795 | ||
| AU565 | HER2amp | Luminal | TAPI-0 | TACE/Collagenase | 0.0533 | uM | 5900.096 | 0.9626 | 0.9727 | 2.7795 | ||
| AU565 | HER2amp | Luminal | TAPI-0 | TACE/Collagenase | 0.267 | uM | 5900.096 | 0.9555 | 0.9675 | 2.7795 | ||
| AU565 | HER2amp | Luminal | TAPI-0 | TACE/Collagenase | 1.33 | uM | 5900.096 | 0.9072 | 0.9311 | 2.7795 | ||
| AU565 | HER2amp | Luminal | TAPI-0 | TACE/Collagenase | 6.67 | uM | 5900.096 | 0.8335 | 0.8731 | 2.7795 | ||
| AU565 | HER2amp | Luminal | TAPI-0 | TACE/Collagenase | 33.3 | uM | 5900.096 | 0.8037 | 0.8488 | 2.7795 | ||
| BT-20 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.0000853 | uM | 5904.096 | 1.1330 | 1.2741 | 0.9724 | ||
| BT-20 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.000427 | uM | 5904.096 | 1.0741 | 1.1525 | 0.9724 |