Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR-75-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7553.067 | 0.9699 | 0.9466 | 1.1302 | |
| ZR-75-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7553.067 | 0.0255 | -0.9222 | 1.1302 | |
| ZR-75-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7553.067 | 0.0079 | -0.9723 | 1.1302 | |
| ZR75B | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7555.067 | 0.9824 | 0.9791 | 1.6890 | |
| ZR75B | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7555.067 | 0.9212 | 0.9052 | 1.6890 | |
| ZR75B | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7555.067 | 0.9687 | 0.9627 | 1.6890 | |
| ZR75B | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7555.067 | 0.9489 | 0.9388 | 1.6890 | |
| ZR75B | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7555.067 | 1.0223 | 1.0263 | 1.6890 | |
| ZR75B | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7555.067 | 0.9411 | 0.9294 | 1.6890 | |
| ZR75B | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7555.067 | 0.7106 | 0.6337 | 1.6890 | |
| ZR75B | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7555.067 | 0.0168 | -0.8219 | 1.6890 | |
| ZR75B | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7555.067 | 1.0467 | 1.0548 | 1.6890 | |
| 184A1 | NM | Basal | TAPI-0 | TACE/Collagenase | 0.0000853 | uM | 5895.096 | 1.0739 | 1.1027 | 1.4232 | ||
| 184A1 | NM | Basal | TAPI-0 | TACE/Collagenase | 0.000427 | uM | 5895.096 | 1.0183 | 1.0257 | 1.4232 | ||
| 184A1 | NM | Basal | TAPI-0 | TACE/Collagenase | 0.00213 | uM | 5895.096 | 1.0760 | 1.1057 | 1.4232 | ||
| 184A1 | NM | Basal | TAPI-0 | TACE/Collagenase | 0.0107 | uM | 5895.096 | 0.9732 | 0.9622 | 1.4232 | ||
| 184A1 | NM | Basal | TAPI-0 | TACE/Collagenase | 0.0533 | uM | 5895.096 | 1.0658 | 1.0916 | 1.4232 | ||
| 184A1 | NM | Basal | TAPI-0 | TACE/Collagenase | 0.267 | uM | 5895.096 | 1.0070 | 1.0099 | 1.4232 | ||
| 184A1 | NM | Basal | TAPI-0 | TACE/Collagenase | 1.33 | uM | 5895.096 | 1.0942 | 1.1305 | 1.4232 | ||
| 184A1 | NM | Basal | TAPI-0 | TACE/Collagenase | 6.67 | uM | 5895.096 | 0.9570 | 0.9391 | 1.4232 | ||
| 184A1 | NM | Basal | TAPI-0 | TACE/Collagenase | 33.3 | uM | 5895.096 | 0.9160 | 0.8804 | 1.4232 | ||
| 184B5 | NM | Basal | TAPI-0 | TACE/Collagenase | 0.0000853 | uM | 5897.096 | 1.0160 | 1.0250 | 1.2810 | ||
| 184B5 | NM | Basal | TAPI-0 | TACE/Collagenase | 0.000427 | uM | 5897.096 | 1.0064 | 1.0100 | 1.2810 | ||
| 184B5 | NM | Basal | TAPI-0 | TACE/Collagenase | 0.00213 | uM | 5897.096 | 0.9990 | 0.9985 | 1.2810 | ||
| 184B5 | NM | Basal | TAPI-0 | TACE/Collagenase | 0.0107 | uM | 5897.096 | 0.9817 | 0.9714 | 1.2810 |