Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7496.067 | 0.0048 | -0.9823 | 1.1301 | |
| MDA-MB-157 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7498.067 | 0.9743 | 0.9546 | 1.1346 | |
| MDA-MB-157 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7498.067 | 0.9843 | 0.9723 | 1.1346 | |
| MDA-MB-157 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7498.067 | 0.9711 | 0.9489 | 1.1346 | |
| MDA-MB-157 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7498.067 | 1.0235 | 1.0414 | 1.1346 | |
| MDA-MB-157 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7498.067 | 1.0437 | 1.0769 | 1.1346 | |
| MDA-MB-157 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7498.067 | 1.0001 | 1.0001 | 1.1346 | |
| MDA-MB-157 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7498.067 | 0.6532 | 0.3742 | 1.1346 | |
| MDA-MB-157 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7498.067 | 0.0175 | -0.9434 | 1.1346 | |
| MDA-MB-157 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7498.067 | 1.0089 | 1.0157 | 1.1346 | |
| MDA-MB-175-VII | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7499.067 | 0.9383 | 0.8424 | 0.7759 | |
| MDA-MB-175-VII | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7499.067 | 0.9950 | 0.9871 | 0.7759 | |
| MDA-MB-175-VII | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7499.067 | 0.9591 | 0.8952 | 0.7759 | |
| MDA-MB-175-VII | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7499.067 | 0.9050 | 0.7586 | 0.7759 | |
| MDA-MB-175-VII | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7499.067 | 0.9806 | 0.9501 | 0.7759 | |
| MDA-MB-175-VII | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7499.067 | 0.8985 | 0.7424 | 0.7759 | |
| MDA-MB-175-VII | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7499.067 | 0.7394 | 0.3554 | 0.7759 | |
| MDA-MB-175-VII | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7499.067 | 0.0020 | -0.9993 | 0.7759 | |
| MDA-MB-175-VII | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7499.067 | 0.0003 | -0.9999 | 0.7759 | |
| MDA-MB-175-VII | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7500.067 | 1.0195 | 1.0547 | 0.7143 | |
| MDA-MB-175-VII | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7500.067 | 1.0224 | 1.0631 | 0.7143 | |
| MDA-MB-175-VII | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7500.067 | 0.9271 | 0.7988 | 0.7143 | |
| MDA-MB-175-VII | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7500.067 | 1.0486 | 1.1373 | 0.7143 | |
| MDA-MB-175-VII | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7500.067 | 1.0975 | 1.2781 | 0.7143 | |
| MDA-MB-175-VII | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7500.067 | 1.0190 | 1.0533 | 0.7143 |