Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 12112.135 | 0.9271 | 0.9185 | 1.8185 | |
| HCC1143 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 12112.135 | 0.8651 | 0.8468 | 1.8185 | |
| HCC1143 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 12112.135 | 0.8047 | 0.7748 | 1.8185 | |
| HCC1187 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 10518.135 | 1.0732 | 1.1273 | 1.1446 | |
| HCC1187 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 10518.135 | 1.0009 | 1.0016 | 1.1446 | |
| HCC1187 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 10518.135 | 1.0326 | 1.0569 | 1.1446 | |
| HCC1187 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 10518.135 | 0.5046 | 0.1002 | 1.1446 | |
| HCC1187 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 10518.135 | 1.0102 | 1.0179 | 1.1446 | |
| HCC1187 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 10518.135 | 1.0774 | 1.1347 | 1.1446 | |
| HCC1187 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 10518.135 | 1.0784 | 1.1363 | 1.1446 | |
| HCC1187 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 10518.135 | 0.9010 | 0.8259 | 1.1446 | |
| HCC1187 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 10518.135 | 0.7143 | 0.4907 | 1.1446 | |
| HCC1187 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.000171 | uM | 10753.148 | 0.9861 | 0.9786 | 1.2988 | |
| HCC1187 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.000853 | uM | 10753.148 | 0.9075 | 0.8559 | 1.2988 | |
| HCC1187 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.00427 | uM | 10753.148 | 1.0012 | 1.0019 | 1.2988 | |
| HCC1187 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.0213 | uM | 10753.148 | 0.9432 | 0.9119 | 1.2988 | |
| HCC1187 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.107 | uM | 10753.148 | 0.9892 | 0.9834 | 1.2988 | |
| HCC1187 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.533 | uM | 10753.148 | 1.0188 | 1.0289 | 1.2988 | |
| HCC1187 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 2.67 | uM | 10753.148 | 1.0193 | 1.0296 | 1.2988 | |
| HCC1187 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 13.3 | uM | 10753.148 | 0.9590 | 0.9365 | 1.2988 | |
| HCC1187 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 66.7 | uM | 10753.148 | 0.7072 | 0.5317 | 1.2988 | |
| HCC1395 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 12000.135 | 1.0218 | 1.0635 | 0.6914 | |
| HCC1395 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 12000.135 | 0.9421 | 0.8346 | 0.6914 | |
| HCC1395 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 12000.135 | 1.0261 | 1.0758 | 0.6914 | |
| HCC1395 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 12000.135 | 0.9650 | 0.8996 | 0.6914 |