Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7543.067 | 0.0005 | -0.9958 | 1.2437 | |
| T47DKBLUC | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7546.067 | 0.9611 | 0.9090 | 0.8509 | |
| T47DKBLUC | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7546.067 | 1.0251 | 1.0591 | 0.8509 | |
| T47DKBLUC | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7546.067 | 0.9919 | 0.9810 | 0.8509 | |
| T47DKBLUC | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7546.067 | 1.0153 | 1.0359 | 0.8509 | |
| T47DKBLUC | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7546.067 | 1.0498 | 1.1176 | 0.8509 | |
| T47DKBLUC | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7546.067 | 1.0076 | 1.0178 | 0.8509 | |
| T47DKBLUC | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7546.067 | 0.8984 | 0.7635 | 0.8509 | |
| T47DKBLUC | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7546.067 | 0.0089 | -0.9923 | 0.8509 | |
| T47DKBLUC | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7546.067 | 0.0075 | -0.9936 | 0.8509 | |
| ZR-75-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7552.067 | 0.9917 | 0.9837 | 1.0224 | |
| ZR-75-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7552.067 | 1.0173 | 1.0339 | 1.0224 | |
| ZR-75-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7552.067 | 1.0272 | 1.0533 | 1.0224 | |
| ZR-75-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7552.067 | 0.9687 | 0.9388 | 1.0224 | |
| ZR-75-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7552.067 | 1.0687 | 1.1343 | 1.0224 | |
| ZR-75-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7552.067 | 0.9952 | 0.9906 | 1.0224 | |
| ZR-75-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7552.067 | 0.9551 | 0.9122 | 1.0224 | |
| ZR-75-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7552.067 | 0.0171 | -0.9627 | 1.0224 | |
| ZR-75-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7552.067 | 0.0092 | -0.9796 | 1.0224 | |
| ZR-75-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7553.067 | 0.9807 | 0.9657 | 1.1302 | |
| ZR-75-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7553.067 | 1.0102 | 1.0180 | 1.1302 | |
| ZR-75-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7553.067 | 0.9893 | 0.9811 | 1.1302 | |
| ZR-75-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7553.067 | 0.9904 | 0.9830 | 1.1302 | |
| ZR-75-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7553.067 | 1.0236 | 1.0418 | 1.1302 | |
| ZR-75-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7553.067 | 1.0269 | 1.0475 | 1.1302 |