Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 10997.135 | 0.9432 | 0.8300 | 0.6582 | |
| MCF7 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 10997.135 | 0.9599 | 0.8793 | 0.6582 | |
| MCF7 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 10997.135 | 0.9899 | 0.9693 | 0.6582 | |
| MCF7 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 10997.135 | 0.9220 | 0.7677 | 0.6582 | |
| MCF7 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 10997.135 | 0.8855 | 0.6626 | 0.6582 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 10519.135 | 1.0420 | 1.0943 | 0.8926 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 10519.135 | 0.9856 | 0.9678 | 0.8926 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 10519.135 | 1.0003 | 1.0008 | 0.8926 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 10519.135 | 0.9741 | 0.9421 | 0.8926 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 10519.135 | 1.0305 | 1.0684 | 0.8926 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 10519.135 | 0.9973 | 0.9938 | 0.8926 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 10519.135 | 1.0883 | 1.1988 | 0.8926 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 10519.135 | 0.9660 | 0.9240 | 0.8926 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 10519.135 | 0.7868 | 0.5289 | 0.8926 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 10998.135 | 0.9668 | 0.8740 | 0.5194 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 10998.135 | 0.9696 | 0.8847 | 0.5194 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 10998.135 | 0.9458 | 0.7966 | 0.5194 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 10998.135 | 0.9590 | 0.8450 | 0.5194 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 10998.135 | 0.9339 | 0.7534 | 0.5194 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 10998.135 | 1.0045 | 1.0174 | 0.5194 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 10998.135 | 0.9884 | 0.9557 | 0.5194 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 10998.135 | 0.9536 | 0.8253 | 0.5194 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 10998.135 | 0.8368 | 0.4193 | 0.5194 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 12206.135 | 1.0080 | 1.0162 | 0.9865 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 12206.135 | 0.9978 | 0.9956 | 0.9865 |