Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.00213 | uM | 5904.096 | 1.0349 | 1.0718 | 0.9724 | ||
| BT-20 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.0107 | uM | 5904.096 | 1.0032 | 1.0065 | 0.9724 | ||
| BT-20 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.0533 | uM | 5904.096 | 1.0492 | 1.1013 | 0.9724 | ||
| BT-20 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 0.267 | uM | 5904.096 | 1.0166 | 1.0342 | 0.9724 | ||
| BT-20 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 1.33 | uM | 5904.096 | 0.9144 | 0.8242 | 0.9724 | ||
| BT-20 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 6.67 | uM | 5904.096 | 0.7355 | 0.4583 | 0.9724 | ||
| BT-20 | TNBC | Basal A | TAPI-0 | TACE/Collagenase | 33.3 | uM | 5904.096 | 0.5926 | 0.1678 | 0.9724 | ||
| BT-474 | HER2amp | Luminal | TAPI-0 | TACE/Collagenase | 0.0000853 | uM | 5905.096 | 1.0494 | 1.1090 | 0.9091 | ||
| BT-474 | HER2amp | Luminal | TAPI-0 | TACE/Collagenase | 0.000427 | uM | 5905.096 | 1.0542 | 1.1195 | 0.9091 | ||
| BT-474 | HER2amp | Luminal | TAPI-0 | TACE/Collagenase | 0.00213 | uM | 5905.096 | 0.9746 | 0.9443 | 0.9091 | ||
| BT-474 | HER2amp | Luminal | TAPI-0 | TACE/Collagenase | 0.0107 | uM | 5905.096 | 0.9605 | 0.9132 | 0.9091 | ||
| BT-474 | HER2amp | Luminal | TAPI-0 | TACE/Collagenase | 0.0533 | uM | 5905.096 | 1.0234 | 1.0516 | 0.9091 | ||
| BT-474 | HER2amp | Luminal | TAPI-0 | TACE/Collagenase | 0.267 | uM | 5905.096 | 1.0215 | 1.0473 | 0.9091 | ||
| BT-474 | HER2amp | Luminal | TAPI-0 | TACE/Collagenase | 1.33 | uM | 5905.096 | 0.9786 | 0.9530 | 0.9091 | ||
| BT-474 | HER2amp | Luminal | TAPI-0 | TACE/Collagenase | 6.67 | uM | 5905.096 | 0.9654 | 0.9240 | 0.9091 | ||
| BT-474 | HER2amp | Luminal | TAPI-0 | TACE/Collagenase | 33.3 | uM | 5905.096 | 0.8538 | 0.6808 | 0.9091 | ||
| BT-549 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 0.0000853 | uM | 5909.096 | 1.0643 | 1.0418 | 3.0117 | ||
| BT-549 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 0.000427 | uM | 5909.096 | 0.9901 | 0.9934 | 3.0117 | ||
| BT-549 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 0.00213 | uM | 5909.096 | 1.0804 | 1.0520 | 3.0117 | ||
| BT-549 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 0.0107 | uM | 5909.096 | 1.0575 | 1.0374 | 3.0117 | ||
| BT-549 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 0.0533 | uM | 5909.096 | 0.9525 | 0.9679 | 3.0117 | ||
| BT-549 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 0.267 | uM | 5909.096 | 1.0058 | 1.0039 | 3.0117 | ||
| BT-549 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 1.33 | uM | 5909.096 | 0.9901 | 0.9934 | 3.0117 | ||
| BT-549 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 6.67 | uM | 5909.096 | 0.8790 | 0.9162 | 3.0117 | ||
| BT-549 | TNBC | Basal B | TAPI-0 | TACE/Collagenase | 33.3 | uM | 5909.096 | 0.8321 | 0.8816 | 3.0117 |