Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7507.067 | 1.0225 | 1.0456 | 0.9880 | |
| MDA-MB-361 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7507.067 | 1.0268 | 1.0542 | 0.9880 | |
| MDA-MB-361 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7507.067 | 0.9601 | 0.9192 | 0.9880 | |
| MDA-MB-361 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7507.067 | 0.0123 | -0.9767 | 0.9880 | |
| MDA-MB-361 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7507.067 | 0.0039 | -0.9927 | 0.9880 | |
| MDA-MB-361 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7508.067 | 0.9514 | 0.8724 | 0.7560 | |
| MDA-MB-361 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7508.067 | 1.0096 | 1.0254 | 0.7560 | |
| MDA-MB-361 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7508.067 | 1.0087 | 1.0230 | 0.7560 | |
| MDA-MB-361 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7508.067 | 1.0123 | 1.0327 | 0.7560 | |
| MDA-MB-361 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7508.067 | 0.9740 | 0.9315 | 0.7560 | |
| MDA-MB-361 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7508.067 | 0.9588 | 0.8917 | 0.7560 | |
| MDA-MB-361 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7508.067 | 0.9510 | 0.8714 | 0.7560 | |
| MDA-MB-361 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7508.067 | 0.0119 | -0.9943 | 0.7560 | |
| MDA-MB-361 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7508.067 | 0.0022 | -0.9994 | 0.7560 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7510.067 | 0.9312 | 0.8362 | 0.8348 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7510.067 | 1.0009 | 1.0022 | 0.8348 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7510.067 | 0.9788 | 0.9494 | 0.8348 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7510.067 | 0.9618 | 0.9089 | 0.8348 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7510.067 | 1.0456 | 1.1099 | 0.8348 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7510.067 | 1.0341 | 1.0821 | 0.8348 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7510.067 | 0.4778 | -0.1744 | 0.8348 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7510.067 | 0.0005 | -0.9998 | 0.8348 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7510.067 | 0.0005 | -0.9998 | 0.8348 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7511.067 | 1.0099 | 1.0175 | 1.1247 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7511.067 | 1.0647 | 1.1147 | 1.1247 |