Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 10580.135 | 0.9646 | 0.9283 | 0.9868 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 10580.135 | 0.9235 | 0.8450 | 0.9868 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 10580.135 | 0.9701 | 0.9395 | 0.9868 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 10580.135 | 0.9190 | 0.8359 | 0.9868 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 10580.135 | 0.9569 | 0.9126 | 0.9868 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 10580.135 | 0.9549 | 0.9086 | 0.9868 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 10580.135 | 0.9290 | 0.8561 | 0.9868 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 10580.135 | 0.9170 | 0.8318 | 0.9868 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 10580.135 | 0.9115 | 0.8208 | 0.9868 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000171 | uM | 10754.148 | 0.9729 | 0.9524 | 1.1406 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000853 | uM | 10754.148 | 0.9315 | 0.8794 | 1.1406 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00427 | uM | 10754.148 | 1.0113 | 1.0198 | 1.1406 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0213 | uM | 10754.148 | 0.9473 | 0.9073 | 1.1406 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.107 | uM | 10754.148 | 0.9227 | 0.8638 | 1.1406 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.533 | uM | 10754.148 | 0.9882 | 0.9793 | 1.1406 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 2.67 | uM | 10754.148 | 0.9074 | 0.8367 | 1.1406 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 13.3 | uM | 10754.148 | 0.9202 | 0.8594 | 1.1406 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 66.7 | uM | 10754.148 | 0.8587 | 0.7499 | 1.1406 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 11938.135 | 0.9191 | 0.7683 | 0.6853 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 11938.135 | 0.9116 | 0.7474 | 0.6853 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 11938.135 | 0.9465 | 0.8457 | 0.6853 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 11938.135 | 0.9613 | 0.8882 | 0.6853 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 11938.135 | 0.8719 | 0.6375 | 0.6853 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 11938.135 | 0.9215 | 0.7752 | 0.6853 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 11938.135 | 0.9754 | 0.9285 | 0.6853 |