Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 11938.135 | 0.9259 | 0.7874 | 0.6853 | |
| UACC-812 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 11938.135 | 0.9211 | 0.7739 | 0.6853 | |
| ZR-75-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000171 | uM | 11660.148 | 0.9748 | 0.9560 | 1.1480 | |
| ZR-75-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000853 | uM | 11660.148 | 0.8851 | 0.7982 | 1.1480 | |
| ZR-75-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00427 | uM | 11660.148 | 0.9120 | 0.8457 | 1.1480 | |
| ZR-75-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0213 | uM | 11660.148 | 0.8955 | 0.8166 | 1.1480 | |
| ZR-75-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.107 | uM | 11660.148 | 0.9144 | 0.8500 | 1.1480 | |
| ZR-75-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.533 | uM | 11660.148 | 0.9534 | 0.9186 | 1.1480 | |
| ZR-75-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 2.67 | uM | 11660.148 | 0.9370 | 0.8897 | 1.1480 | |
| ZR-75-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 13.3 | uM | 11660.148 | 0.9265 | 0.8714 | 1.1480 | |
| ZR-75-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 66.7 | uM | 11660.148 | 0.6983 | 0.4628 | 1.1480 | |
| ZR-75-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 12003.135 | 0.9573 | 0.9138 | 0.9898 | |
| ZR-75-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 12003.135 | 0.8993 | 0.7966 | 0.9898 | |
| ZR-75-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 12003.135 | 0.9745 | 0.9484 | 0.9898 | |
| ZR-75-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 12003.135 | 0.9200 | 0.8384 | 0.9898 | |
| ZR-75-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 12003.135 | 0.9565 | 0.9121 | 0.9898 | |
| ZR-75-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 12003.135 | 0.9446 | 0.8880 | 0.9898 | |
| ZR-75-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 12003.135 | 0.9476 | 0.8940 | 0.9898 | |
| ZR-75-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 12003.135 | 0.9255 | 0.8495 | 0.9898 | |
| ZR-75-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 12003.135 | 0.6501 | 0.2944 | 0.9898 | |
| ZR75B | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 11939.135 | 0.9617 | 0.9517 | 1.5987 | |
| ZR75B | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 11939.135 | 0.9277 | 0.9083 | 1.5987 | |
| ZR75B | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 11939.135 | 0.9674 | 0.9590 | 1.5987 | |
| ZR75B | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 11939.135 | 0.9903 | 0.9879 | 1.5987 | |
| ZR75B | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 11939.135 | 0.9195 | 0.8977 | 1.5987 |