Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 11852.135 | 1.0990 | 1.1573 | 1.2467 | |
| SUM52PE | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 11852.135 | 1.0834 | 1.1327 | 1.2467 | |
| SUM52PE | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 11852.135 | 1.0902 | 1.1434 | 1.2467 | |
| SUM52PE | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 11852.135 | 1.0620 | 1.0989 | 1.2467 | |
| SUM52PE | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 11852.135 | 1.0370 | 1.0592 | 1.2467 | |
| SUM52PE | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 11852.135 | 0.6928 | 0.4900 | 1.2467 | |
| SUM52PE | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 11852.135 | 0.4239 | 0.0047 | 1.2467 | |
| T47D | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000171 | uM | 10939.148 | 0.9530 | 0.9428 | 1.6568 | |
| T47D | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000853 | uM | 10939.148 | 1.0111 | 1.0134 | 1.6568 | |
| T47D | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00427 | uM | 10939.148 | 0.9557 | 0.9461 | 1.6568 | |
| T47D | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0213 | uM | 10939.148 | 0.9768 | 0.9719 | 1.6568 | |
| T47D | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.107 | uM | 10939.148 | 0.9642 | 0.9564 | 1.6568 | |
| T47D | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.533 | uM | 10939.148 | 1.0221 | 1.0265 | 1.6568 | |
| T47D | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 2.67 | uM | 10939.148 | 0.9912 | 0.9893 | 1.6568 | |
| T47D | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 13.3 | uM | 10939.148 | 0.9240 | 0.9068 | 1.6568 | |
| T47D | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 66.7 | uM | 10939.148 | 0.8014 | 0.7498 | 1.6568 | |
| T47DKBLUC | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 12608.135 | 0.9716 | 0.9542 | 1.2417 | |
| T47DKBLUC | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 12608.135 | 0.9685 | 0.9490 | 1.2417 | |
| T47DKBLUC | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 12608.135 | 0.9536 | 0.9249 | 1.2417 | |
| T47DKBLUC | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 12608.135 | 0.9564 | 0.9294 | 1.2417 | |
| T47DKBLUC | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 12608.135 | 0.9601 | 0.9356 | 1.2417 | |
| T47DKBLUC | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 12608.135 | 0.9907 | 0.9850 | 1.2417 | |
| T47DKBLUC | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 12608.135 | 1.0002 | 1.0003 | 1.2417 | |
| T47DKBLUC | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 12608.135 | 1.0066 | 1.0106 | 1.2417 | |
| T47DKBLUC | Unknown | Unknown | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 12608.135 | 0.9645 | 0.9426 | 1.2417 |