Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | Temsirolimus | MTOR | MTOR | 1.07 | uM | 11055.144 | 0.5509 | 0.3999 | 1.6716 | |
| HCC1954 | HER2amp | Basal A | Temsirolimus | MTOR | MTOR | 5.33 | uM | 11055.144 | 0.5764 | 0.4384 | 1.6716 | |
| HCC1954 | HER2amp | Basal A | Temsirolimus | MTOR | MTOR | 26.7 | uM | 11055.144 | 0.4976 | 0.3174 | 1.6716 | |
| HCC1954 | HER2amp | Basal A | Temsirolimus | MTOR | MTOR | 133 | uM | 11055.144 | 0.0070 | -0.8972 | 1.6716 | |
| HCC2185 | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 10996.144 | 0.9181 | 0.6923 | 0.5116 | |
| HCC2185 | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 10996.144 | 0.9506 | 0.8115 | 0.5116 | |
| HCC2185 | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 10996.144 | 0.8378 | 0.4150 | 0.5116 | |
| HCC2185 | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 10996.144 | 0.6773 | -0.0662 | 0.5116 | |
| HCC2185 | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 0.213 | uM | 10996.144 | 0.6599 | -0.1124 | 0.5116 | |
| HCC2185 | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 1.07 | uM | 10996.144 | 0.6267 | -0.1976 | 0.5116 | |
| HCC2185 | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 5.33 | uM | 10996.144 | 0.6400 | -0.1639 | 0.5116 | |
| HCC2185 | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 26.7 | uM | 10996.144 | 0.4995 | -0.4850 | 0.5116 | |
| HCC2185 | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 133 | uM | 10996.144 | 0.0102 | -0.9997 | 0.5116 | |
| HCC2185 | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 12192.144 | 0.9551 | 0.8477 | 0.5798 | |
| HCC2185 | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 12192.144 | 0.9083 | 0.6943 | 0.5798 | |
| HCC2185 | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 12192.144 | 0.7950 | 0.3465 | 0.5798 | |
| HCC2185 | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 0.0427 | uM | 12192.144 | 0.6743 | 0.0135 | 0.5798 | |
| HCC2185 | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 0.213 | uM | 12192.144 | 0.6057 | -0.1577 | 0.5798 | |
| HCC2185 | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 1.07 | uM | 12192.144 | 0.5837 | -0.2098 | 0.5798 | |
| HCC2185 | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 5.33 | uM | 12192.144 | 0.6355 | -0.0851 | 0.5798 | |
| HCC2185 | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 26.7 | uM | 12192.144 | 0.5387 | -0.3120 | 0.5798 | |
| HCC2185 | TNBC | Luminal | Temsirolimus | MTOR | MTOR | 133 | uM | 12192.144 | 0.2392 | -0.8304 | 0.5798 | |
| HCC3153 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 0.000341 | uM | 10577.144 | 0.9571 | 0.9101 | 0.9534 | |
| HCC3153 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 0.00171 | uM | 10577.144 | 0.8760 | 0.7406 | 0.9534 | |
| HCC3153 | TNBC | Basal A | Temsirolimus | MTOR | MTOR | 0.00853 | uM | 10577.144 | 0.7931 | 0.5684 | 0.9534 |