Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.0213 | uM | 5898.093 | 0.9427 | 0.8374 | 0.6963 | |
| 600MPE | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.107 | uM | 5898.093 | 0.9975 | 0.9929 | 0.6963 | |
| 600MPE | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.533 | uM | 5898.093 | 0.9797 | 0.9420 | 0.6963 | |
| 600MPE | HR+ | Luminal | TPCA-1 | IKK | NFKB | 2.67 | uM | 5898.093 | 1.0237 | 1.0684 | 0.6963 | |
| 600MPE | HR+ | Luminal | TPCA-1 | IKK | NFKB | 13.3 | uM | 5898.093 | 0.8457 | 0.5720 | 0.6963 | |
| 600MPE | HR+ | Luminal | TPCA-1 | IKK | NFKB | 66.7 | uM | 5898.093 | 0.8515 | 0.5876 | 0.6963 | |
| AU565 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.000171 | uM | 5900.093 | 0.9845 | 0.9865 | 2.3084 | |
| AU565 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.000853 | uM | 5900.093 | 1.0256 | 1.0220 | 2.3084 | |
| AU565 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.00427 | uM | 5900.093 | 0.9939 | 0.9947 | 2.3084 | |
| AU565 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.0213 | uM | 5900.093 | 1.0043 | 1.0037 | 2.3084 | |
| AU565 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.107 | uM | 5900.093 | 1.0113 | 1.0098 | 2.3084 | |
| AU565 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 0.533 | uM | 5900.093 | 0.9345 | 0.9422 | 2.3084 | |
| AU565 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 2.67 | uM | 5900.093 | 0.7608 | 0.7767 | 2.3084 | |
| AU565 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 13.3 | uM | 5900.093 | 0.7168 | 0.7314 | 2.3084 | |
| AU565 | HER2amp | Luminal | TPCA-1 | IKK | NFKB | 66.7 | uM | 5900.093 | 0.7542 | 0.7699 | 2.3084 | |
| BT-20 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.000341 | uM | 5904.1 | 1.0093 | 1.0139 | 1.3369 | |
| BT-20 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.00171 | uM | 5904.1 | 0.9160 | 0.8729 | 1.3369 | |
| BT-20 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.00853 | uM | 5904.1 | 0.9507 | 0.9258 | 1.3369 | |
| BT-20 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.0427 | uM | 5904.1 | 0.9089 | 0.8621 | 1.3369 | |
| BT-20 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.213 | uM | 5904.1 | 1.0475 | 1.0707 | 1.3369 | |
| BT-20 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 1.07 | uM | 5904.1 | 0.8686 | 0.8001 | 1.3369 | |
| BT-20 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 5.33 | uM | 5904.1 | 0.6387 | 0.4301 | 1.3369 | |
| BT-20 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 26.7 | uM | 5904.1 | 0.8452 | 0.7636 | 1.3369 | |
| BT-20 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 133 | uM | 5904.1 | 0.6043 | 0.3721 | 1.3369 | |
| BT-20 | TNBC | Basal A | TPCA-1 | IKK | NFKB | 0.000171 | uM | 10385.093 | 0.9571 | 0.8609 | 0.6082 |