Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.267 | uM | 12702.002 | 0.0780 | -0.4885 | 1.8712 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 1.33 | uM | 12702.002 | 0.0604 | -0.5538 | 1.8712 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 6.67 | uM | 12702.002 | 0.0597 | -0.5565 | 1.8712 | |
| HCC1806 | TNBC | Basal A | Taxol | TUBB | TUBB | 33.3 | uM | 12702.002 | 0.0650 | -0.5359 | 1.8712 | |
| HCC1937 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0000853 | uM | 10262.002 | 1.0708 | 1.2273 | 0.6356 | |
| HCC1937 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.000427 | uM | 10262.002 | 1.0742 | 1.2384 | 0.6356 | |
| HCC1937 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.00213 | uM | 10262.002 | 1.0245 | 1.0775 | 0.6356 | |
| HCC1937 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0107 | uM | 10262.002 | 0.8614 | 0.5816 | 0.6356 | |
| HCC1937 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0533 | uM | 10262.002 | 0.6287 | -0.0362 | 0.6356 | |
| HCC1937 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.267 | uM | 10262.002 | 0.6080 | -0.0858 | 0.6356 | |
| HCC1937 | TNBC | Basal A | Taxol | TUBB | TUBB | 1.33 | uM | 10262.002 | 0.5997 | -0.1053 | 0.6356 | |
| HCC1937 | TNBC | Basal A | Taxol | TUBB | TUBB | 6.67 | uM | 10262.002 | 0.5862 | -0.1368 | 0.6356 | |
| HCC1937 | TNBC | Basal A | Taxol | TUBB | TUBB | 33.3 | uM | 10262.002 | 0.4352 | -0.4597 | 0.6356 | |
| HCC1954 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.0000853 | uM | 7837.002 | 1.0076 | 1.0088 | 1.7373 | |
| HCC1954 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.000427 | uM | 7837.002 | 0.8762 | 0.8536 | 1.7373 | |
| HCC1954 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.00213 | uM | 7837.002 | 1.0083 | 1.0095 | 1.7373 | |
| HCC1954 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.0107 | uM | 7837.002 | 0.7678 | 0.7178 | 1.7373 | |
| HCC1954 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.0533 | uM | 7837.002 | 0.1088 | -0.4422 | 1.7373 | |
| HCC1954 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.267 | uM | 7837.002 | 0.0380 | -0.6954 | 1.7373 | |
| HCC1954 | HER2amp | Basal A | Taxol | TUBB | TUBB | 1.33 | uM | 7837.002 | 0.0411 | -0.6816 | 1.7373 | |
| HCC1954 | HER2amp | Basal A | Taxol | TUBB | TUBB | 6.67 | uM | 7837.002 | 0.0488 | -0.6485 | 1.7373 | |
| HCC1954 | HER2amp | Basal A | Taxol | TUBB | TUBB | 33.3 | uM | 7837.002 | 0.0525 | -0.6333 | 1.7373 | |
| HCC1954 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.0000853 | uM | 7839.002 | 1.2108 | 1.2381 | 1.7009 | |
| HCC1954 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.000427 | uM | 7839.002 | 1.0320 | 1.0374 | 1.7009 | |
| HCC1954 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.00213 | uM | 7839.002 | 1.0044 | 1.0051 | 1.7009 |