Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 10031.002 | 1.0436 | 1.1361 | 0.6483 | |
| HCC1428 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 10031.002 | 0.9951 | 0.9849 | 0.6483 | |
| HCC1428 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 10031.002 | 1.0591 | 1.1852 | 0.6483 | |
| HCC1428 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 10031.002 | 0.9387 | 0.8141 | 0.6483 | |
| HCC1428 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 10031.002 | 0.8673 | 0.6056 | 0.6483 | |
| HCC1428 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 10031.002 | 0.8409 | 0.5308 | 0.6483 | |
| HCC1428 | HR+ | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 10031.002 | 0.8330 | 0.5088 | 0.6483 | |
| HCC1428 | HR+ | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 10031.002 | 0.8403 | 0.5291 | 0.6483 | |
| HCC1428 | HR+ | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 10031.002 | 0.8262 | 0.4898 | 0.6483 | |
| HCC1569 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.0000853 | uM | 9347.002 | 1.0376 | 1.0502 | 1.4904 | |
| HCC1569 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.000427 | uM | 9347.002 | 1.0198 | 1.0265 | 1.4904 | |
| HCC1569 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.00213 | uM | 9347.002 | 1.0208 | 1.0278 | 1.4904 | |
| HCC1569 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.0107 | uM | 9347.002 | 0.7318 | 0.6220 | 1.4904 | |
| HCC1569 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.0533 | uM | 9347.002 | 0.5787 | 0.3856 | 1.4904 | |
| HCC1569 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.267 | uM | 9347.002 | 0.6128 | 0.4398 | 1.4904 | |
| HCC1569 | HER2amp | Basal A | Taxol | TUBB | TUBB | 1.33 | uM | 9347.002 | 0.6103 | 0.4359 | 1.4904 | |
| HCC1569 | HER2amp | Basal A | Taxol | TUBB | TUBB | 6.67 | uM | 9347.002 | 0.6313 | 0.4690 | 1.4904 | |
| HCC1569 | HER2amp | Basal A | Taxol | TUBB | TUBB | 33.3 | uM | 9347.002 | 0.5668 | 0.3664 | 1.4904 | |
| HCC1569 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.0000853 | uM | 13038.002 | 1.0941 | 1.1550 | 1.2045 | |
| HCC1569 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.000427 | uM | 13038.002 | 0.9681 | 0.9469 | 1.2045 | |
| HCC1569 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.00213 | uM | 13038.002 | 1.0245 | 1.0406 | 1.2045 | |
| HCC1569 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.0107 | uM | 13038.002 | 0.7472 | 0.5702 | 1.2045 | |
| HCC1569 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.0533 | uM | 13038.002 | 0.5165 | 0.1557 | 1.2045 | |
| HCC1569 | HER2amp | Basal A | Taxol | TUBB | TUBB | 0.267 | uM | 13038.002 | 0.5006 | 0.1260 | 1.2045 | |
| HCC1569 | HER2amp | Basal A | Taxol | TUBB | TUBB | 1.33 | uM | 13038.002 | 0.5322 | 0.1848 | 1.2045 |