Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
HCC1419	HER2amp	Luminal	Sigma A6730	AKT	AKT	0.0213	uM	12001.165	0.9276	0.7393	0.5382
HCC1419	HER2amp	Luminal	Sigma A6730	AKT	AKT	0.107	uM	12001.165	0.9284	0.7422	0.5382
HCC1419	HER2amp	Luminal	Sigma A6730	AKT	AKT	0.533	uM	12001.165	0.9250	0.7302	0.5382
HCC1419	HER2amp	Luminal	Sigma A6730	AKT	AKT	2.67	uM	12001.165	0.7144	0.0706	0.5382
HCC1419	HER2amp	Luminal	Sigma A6730	AKT	AKT	13.3	uM	12001.165	0.4614	-0.5248	0.5382
HCC1419	HER2amp	Luminal	Sigma A6730	AKT	AKT	66.7	uM	12001.165	0.1206	-0.9607	0.5382
HCC1428	HR+	Luminal	Sigma A6730	AKT	AKT	0.000171	uM	10693.153	0.9712	0.9293	0.8137
HCC1428	HR+	Luminal	Sigma A6730	AKT	AKT	0.000853	uM	10693.153	0.9170	0.7979	0.8137
HCC1428	HR+	Luminal	Sigma A6730	AKT	AKT	0.00427	uM	10693.153	0.9614	0.9056	0.8137
HCC1428	HR+	Luminal	Sigma A6730	AKT	AKT	0.0213	uM	10693.153	0.9738	0.9359	0.8137
HCC1428	HR+	Luminal	Sigma A6730	AKT	AKT	0.107	uM	10693.153	0.9642	0.9123	0.8137
HCC1428	HR+	Luminal	Sigma A6730	AKT	AKT	0.533	uM	10693.153	0.9350	0.8415	0.8137
HCC1428	HR+	Luminal	Sigma A6730	AKT	AKT	2.67	uM	10693.153	0.8179	0.5621	0.8137
HCC1428	HR+	Luminal	Sigma A6730	AKT	AKT	13.3	uM	10693.153	0.5399	-0.0623	0.8137
HCC1428	HR+	Luminal	Sigma A6730	AKT	AKT	66.7	uM	10693.153	0.0203	-0.9834	0.8137
HCC1428	HR+	Luminal	Sigma A6730	AKT	AKT	0.000171	uM	11936.158	0.9301	0.8139	0.7417
HCC1428	HR+	Luminal	Sigma A6730	AKT	AKT	0.000853	uM	11936.158	0.8747	0.6696	0.7417
HCC1428	HR+	Luminal	Sigma A6730	AKT	AKT	0.00427	uM	11936.158	0.9515	0.8704	0.7417
HCC1428	HR+	Luminal	Sigma A6730	AKT	AKT	0.0213	uM	11936.158	0.9551	0.8799	0.7417
HCC1428	HR+	Luminal	Sigma A6730	AKT	AKT	0.107	uM	11936.158	0.9587	0.8895	0.7417
HCC1428	HR+	Luminal	Sigma A6730	AKT	AKT	0.533	uM	11936.158	0.9257	0.8022	0.7417
HCC1428	HR+	Luminal	Sigma A6730	AKT	AKT	2.67	uM	11936.158	0.8301	0.5558	0.7417
HCC1428	HR+	Luminal	Sigma A6730	AKT	AKT	13.3	uM	11936.158	0.5629	-0.0783	0.7417
HCC1428	HR+	Luminal	Sigma A6730	AKT	AKT	66.7	uM	11936.158	0.0209	-0.9891	0.7417
HCC1569	HER2amp	Basal A	Sigma A6730	AKT	AKT	0.000171	uM	10872.153	0.9440	0.9273	1.5576

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)