Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 5905.067 | 0.9853 | 0.9632 | 0.7991 | |
| BT-474 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 5905.067 | 1.0432 | 1.1088 | 0.7991 | |
| BT-474 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 5905.067 | 1.0566 | 1.1426 | 0.7991 | |
| BT-474 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 5905.067 | 1.0735 | 1.1857 | 0.7991 | |
| BT-474 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 5905.067 | 1.0153 | 1.0385 | 0.7991 | |
| BT-474 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 5905.067 | 0.9800 | 0.9499 | 0.7991 | |
| BT-474 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 5905.067 | 0.0104 | -0.9934 | 0.7991 | |
| BT-474 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 5905.067 | 0.0018 | -0.9993 | 0.7991 | |
| BT-474 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 5906.067 | 1.0035 | 1.0104 | 0.6838 | |
| BT-474 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 5906.067 | 1.0400 | 1.1180 | 0.6838 | |
| BT-474 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 5906.067 | 1.0171 | 1.0502 | 0.6838 | |
| BT-474 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 5906.067 | 1.0343 | 1.1013 | 0.6838 | |
| BT-474 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 5906.067 | 1.0359 | 1.1058 | 0.6838 | |
| BT-474 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 5906.067 | 1.0787 | 1.2343 | 0.6838 | |
| BT-474 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 5906.067 | 1.0406 | 1.1199 | 0.6838 | |
| BT-474 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 5906.067 | 0.0414 | -0.9810 | 0.6838 | |
| BT-474 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 5906.067 | 0.0082 | -0.9982 | 0.6838 | |
| BT-483 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 5908.067 | 0.9290 | 0.7330 | 0.5143 | |
| BT-483 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 5908.067 | 0.8903 | 0.5957 | 0.5143 | |
| BT-483 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 5908.067 | 0.9473 | 0.8002 | 0.5143 | |
| BT-483 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 5908.067 | 0.9085 | 0.6596 | 0.5143 | |
| BT-483 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 5908.067 | 0.9263 | 0.7235 | 0.5143 | |
| BT-483 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 5908.067 | 0.9176 | 0.6921 | 0.5143 | |
| BT-483 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 5908.067 | 0.9615 | 0.8529 | 0.5143 | |
| BT-483 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 5908.067 | 0.0355 | -0.9970 | 0.5143 |