Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 5902.067 | 1.0295 | 1.0501 | 1.1750 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 5902.067 | 1.0610 | 1.1034 | 1.1750 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 5902.067 | 1.0652 | 1.1104 | 1.1750 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 5902.067 | 1.0078 | 1.0133 | 1.1750 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 5902.067 | 0.0131 | -0.9501 | 1.1750 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 5902.067 | 0.0043 | -0.9807 | 1.1750 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 5903.067 | 0.9799 | 0.9680 | 1.2584 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 5903.067 | 0.9942 | 0.9908 | 1.2584 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 5903.067 | 0.9580 | 0.9329 | 1.2584 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 5903.067 | 1.0252 | 1.0399 | 1.2584 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 5903.067 | 0.9732 | 0.9573 | 1.2584 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 5903.067 | 0.9540 | 0.9265 | 1.2584 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 5903.067 | 0.8484 | 0.7551 | 1.2584 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 5903.067 | 0.0121 | -0.9401 | 1.2584 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 5903.067 | 0.0009 | -0.9924 | 1.2584 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 5904.067 | 0.9376 | 0.8799 | 1.0398 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 5904.067 | 0.9665 | 0.9356 | 1.0398 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 5904.067 | 0.9218 | 0.8493 | 1.0398 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 5904.067 | 1.0135 | 1.0260 | 1.0398 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 5904.067 | 1.1325 | 1.2542 | 1.0398 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 5904.067 | 1.0659 | 1.1266 | 1.0398 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 5904.067 | 1.0046 | 1.0088 | 1.0398 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 5904.067 | 0.0059 | -0.9855 | 1.0398 | |
| BT-20 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 5904.067 | 0.0008 | -0.9979 | 1.0398 | |
| BT-474 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 5905.067 | 0.9529 | 0.8829 | 0.7991 |