Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MCF12A	NM	Basal B	TCS 2312	CHK1	CHK	0.000427	uM	10817.152	0.9967	0.9954	1.4414
MCF12A	NM	Basal B	TCS 2312	CHK1	CHK	0.00213	uM	10817.152	0.9850	0.9791	1.4414
MCF12A	NM	Basal B	TCS 2312	CHK1	CHK	0.0107	uM	10817.152	1.0372	1.0513	1.4414
MCF12A	NM	Basal B	TCS 2312	CHK1	CHK	0.0533	uM	10817.152	1.0305	1.0421	1.4414
MCF12A	NM	Basal B	TCS 2312	CHK1	CHK	0.267	uM	10817.152	0.9446	0.9224	1.4414
MCF12A	NM	Basal B	TCS 2312	CHK1	CHK	1.33	uM	10817.152	0.6012	0.4051	1.4414
MCF12A	NM	Basal B	TCS 2312	CHK1	CHK	6.67	uM	10817.152	0.2275	-0.2840	1.4414
MCF12A	NM	Basal B	TCS 2312	CHK1	CHK	33.3	uM	10817.152	0.1750	-0.4032	1.4414
MCF12A	NM	Basal B	TCS 2312	CHK1	CHK	0.0000853	uM	12365.152	1.0338	1.0317	2.1145
MCF12A	NM	Basal B	TCS 2312	CHK1	CHK	0.000427	uM	12365.152	0.8902	0.8929	2.1145
MCF12A	NM	Basal B	TCS 2312	CHK1	CHK	0.00213	uM	12365.152	0.9660	0.9676	2.1145
MCF12A	NM	Basal B	TCS 2312	CHK1	CHK	0.0107	uM	12365.152	1.0338	1.0317	2.1145
MCF12A	NM	Basal B	TCS 2312	CHK1	CHK	0.0533	uM	12365.152	1.0112	1.0106	2.1145
MCF12A	NM	Basal B	TCS 2312	CHK1	CHK	0.267	uM	12365.152	0.6759	0.6618	2.1145
MCF12A	NM	Basal B	TCS 2312	CHK1	CHK	1.33	uM	12365.152	0.3098	0.1491	2.1145
MCF12A	NM	Basal B	TCS 2312	CHK1	CHK	6.67	uM	12365.152	0.0527	-0.5027	2.1145
MCF12A	NM	Basal B	TCS 2312	CHK1	CHK	33.3	uM	12365.152	0.0537	-0.4981	2.1145
MCF7	HR+	Luminal	TCS 2312	CHK1	CHK	0.0000853	uM	10997.152	0.9829	0.9753	1.3917
MCF7	HR+	Luminal	TCS 2312	CHK1	CHK	0.000427	uM	10997.152	0.9201	0.8838	1.3917
MCF7	HR+	Luminal	TCS 2312	CHK1	CHK	0.00213	uM	10997.152	0.9863	0.9803	1.3917
MCF7	HR+	Luminal	TCS 2312	CHK1	CHK	0.0107	uM	10997.152	1.0427	1.0610	1.3917
MCF7	HR+	Luminal	TCS 2312	CHK1	CHK	0.0533	uM	10997.152	0.9517	0.9301	1.3917
MCF7	HR+	Luminal	TCS 2312	CHK1	CHK	0.267	uM	10997.152	0.8976	0.8506	1.3917
MCF7	HR+	Luminal	TCS 2312	CHK1	CHK	1.33	uM	10997.152	0.6127	0.4066	1.3917
MCF7	HR+	Luminal	TCS 2312	CHK1	CHK	6.67	uM	10997.152	0.0891	-0.6482	1.3917

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)