Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 33.3 | uM | 10997.152 | 0.0323 | -0.8302 | 1.3917 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 10519.14 | 1.0186 | 1.0362 | 1.0269 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 10519.14 | 0.9762 | 0.9536 | 1.0269 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 10519.14 | 0.9927 | 0.9858 | 1.0269 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 10519.14 | 1.0039 | 1.0076 | 1.0269 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 10519.14 | 1.0092 | 1.0179 | 1.0269 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.267 | uM | 10519.14 | 1.0095 | 1.0185 | 1.0269 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 1.33 | uM | 10519.14 | 0.9061 | 0.8169 | 1.0269 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 6.67 | uM | 10519.14 | 0.3628 | -0.2549 | 1.0269 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 33.3 | uM | 10519.14 | 0.4628 | -0.0555 | 1.0269 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 10998.152 | 0.9568 | 0.8989 | 0.8517 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 10998.152 | 0.9574 | 0.9004 | 0.8517 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 10998.152 | 1.0072 | 1.0170 | 0.8517 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 10998.152 | 1.0379 | 1.0892 | 0.8517 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 10998.152 | 0.9688 | 0.9270 | 0.8517 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.267 | uM | 10998.152 | 1.0094 | 1.0221 | 0.8517 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 1.33 | uM | 10998.152 | 0.8130 | 0.5685 | 0.8517 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 6.67 | uM | 10998.152 | 0.4809 | -0.1533 | 0.8517 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 33.3 | uM | 10998.152 | 0.3825 | -0.3529 | 0.8517 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0000853 | uM | 12206.159 | 0.9339 | 0.8767 | 1.0742 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.000427 | uM | 12206.159 | 0.8909 | 0.7960 | 1.0742 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.00213 | uM | 12206.159 | 0.9336 | 0.8761 | 1.0742 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0107 | uM | 12206.159 | 0.9738 | 0.9512 | 1.0742 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.0533 | uM | 12206.159 | 0.9654 | 0.9356 | 1.0742 | |
| MDA-MB-134-VI | HR+ | Luminal | TCS 2312 | CHK1 | CHK | 0.267 | uM | 12206.159 | 0.9471 | 0.9012 | 1.0742 |